Clinical significance of untreated Candida species isolated from ascites in cirrhotic patients

Scandinavian Journal of Infectious Diseases
Sang-Ho ChoiNam Joong Kim

Abstract

The clinical significance of Candida species isolated from cirrhotic ascites is still unknown. We reviewed the clinical and laboratory features of all cirrhotic patients whose ascites samples were positive for Candida species. A total of 21 cirrhotic patients was identified. Patients were regarded as having peritonitis if they had 1 or more clinical symptom(s) or sign(s) in the absence of any other possible explanation. 10 patients (47.6%) were classified into the spontaneous Candida peritonitis (SCP) group, and the remaining 11 patients (52.4%) were classified into asymptomatic candidascites. Mortalities were higher in the SCP group at discharge (50.0% vs 27.3%), 6-month (90% vs 45.5%) and 1-y (100% vs 54.5%) (p=0.007). Receiver-operating characteristic curve analysis revealed that the cut-off value of ascitic fluid polymorphonuclear cell count of 315/mm(3) (0.315 x 10(9)/l) had the highest diagnostic accuracy with both sensitivity and specificity of 1.0. In conclusion, Candida species are associated with a grave outcome when manifested with peritonitis.

Citations

Oct 29, 2009·Surgical Infections·Addison K MayUNKNOWN Surgical Infection Society
Jul 20, 2011·Surgical Infections·Gina M Howell, Matthew R Rosengart
Jun 19, 2010·Internal Medicine·Taro Shimizu, Yasuharu Tokuda
Oct 31, 2007·Journal of Medical Case Reports·Thayur R MadhusudhanIan C Smith
Aug 21, 2009·Journal of Burn Care & Research : Official Publication of the American Burn Association·Frederick W EndorfMatthew B Klein
Mar 1, 2008·Expert Opinion on Medical Diagnostics·Andrew C SteerJonathan R Carapetis
Jun 15, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anna LinnérAnna Norrby-Teglund
Jan 17, 2015·Frontiers in Surgery·Evangelos P MisiakosAnastasios Machairas
May 31, 2015·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Punit J ShahAnna Kabakov
Jun 1, 2018·The Cochrane Database of Systematic Reviews·Camille HuaLaurence Le Cleach
Jul 22, 2018·Revista Brasileira De Ortopedia·Nivaldo Cardozo FilhoDaniel Alencar
Jan 27, 2006·Expert Opinion on Biological Therapy·Michael H YoungDavid M Aronoff
Sep 29, 2007·Cellular Microbiology·Lisa I PåhlmanAnna Norrby-Teglund
Nov 1, 2008·Pediatric Annals·Alexander K C LeungH Dele Davies
Nov 1, 2007·Dermatologic Therapy·Anthony P Fernandez, Francisco A Kerdel
Mar 7, 2007·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Lene KrenkMaria E Christensen
Nov 21, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D ThomasT Ferry
Oct 24, 2012·Clinical Obstetrics and Gynecology·Bassam H RimawiDavid A Eschenbach
Jan 19, 2016·Current Opinion in Infectious Diseases·Christian Eckmann
Apr 24, 2016·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·M KrügerO Schega
Jul 20, 2016·BioMed Research International·Arifa MehreenNajma Arshad
Jan 25, 2020·The Journal of Bone and Joint Surgery. American Volume·Alexander A HysongJonathan G Schoenecker
Sep 3, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S Y HwangH-S Lee
May 3, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jonathan R CarapetisRoss Andrews
Jan 28, 2012·Current Infectious Disease Reports·Haldun Oguz, M Sinan Yilmaz
Aug 3, 2016·Surgical Infections·Brian G Harbrecht, Nick A Nash
Aug 11, 2017·Proceedings of the National Academy of Sciences of the United States of America·Joseph J ZeppaJohn K McCormick
May 23, 2020·Emerging Infectious Diseases·Aliza CookGuliz Erdem
Jan 11, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Trond BruunUNKNOWN INFECT Study Group
Aug 29, 2006·Current Infectious Disease Reports·Donald C Vinh, John M Embil
Sep 30, 2015·The International Journal of Lower Extremity Wounds·Elisabetta IacopiAlberto Piaggesi
Nov 19, 2010·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·E García-CasaresS Molinos Abós
Sep 18, 2010·Head & Neck·Henning WolfTherese Ovesen
Apr 9, 2015·Mycoses·Derek N BremmerRyan K Shields
Sep 30, 2016·World Journal of Gastroenterology : WJG·Marco Fiore, Sebastiano Leone
May 8, 2014·Ophthalmic Plastic and Reconstructive Surgery·Lindsay A Stone, Raymond J Harshbarger
Sep 14, 2017·Proceedings of the National Academy of Sciences of the United States of America·Nikolai Siemens, Anna Norrby-Teglund

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