Clinical signs for identification of neurocysticercosis in swine naturally infected with Taenia solium

Parasitology International
Kashi N PrasadRakesh K Gupta

Abstract

Taenia solium infection is a zoonotic disease and swine is the natural intermediate host. Till date no literatures have described clinical signs in swine indicative of brain involvement by cysticerci. In the present study we describe such clinical signs of porcine neurocysticercosis (NCC). These signs were excessive salivation, excessive blinking and tearing, and subconjunctival nodule. A total of 30 swine (18 with 2 or all 3 clinical signs and 12 without any sign) underwent magnetic resonance imaging (MRI). All 18 swine with above signs had NCC on MRI along with variable involvement of other organs that were subsequently confirmed by ex vivo MRI, necropsy and histopathology, while none of the 12 animals without any sign had NCC. As development of a porcine NCC model has proved difficult, we propose that naturally infected swine can be identified on the basis of these clinical signs and thus used as a model for further research on NCC.

References

Aug 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·M J ChandyS M Chandi
Oct 19, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C BernR H Gilman

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Citations

Oct 31, 2007·Tropical Animal Health and Production·Anand PrakashRam Kumar
Feb 12, 2009·Journal of Biosciences·Kashi Nath PrasadAloukick Kumar Singh
Nov 5, 2013·International Journal for Parasitology·Aloukick K SinghNuzhat Husain
Sep 4, 2015·International Journal for Parasitology·Aloukick K SinghKashi N Prasad
Mar 21, 2016·Veterinary Parasitology·Chiara TrevisanMaria V Johansen
Apr 4, 2008·Tropical Medicine & International Health : TM & IH·B SáenzA Fleury
Jul 29, 2015·The American Journal of Pathology·Manuela R VerasteguiRobert H Gilman
Jun 13, 2018·The American Journal of Tropical Medicine and Hygiene·Karen A Alroy For The Cysticercosis Working Group In Peru
Nov 16, 2018·Parasitology·Anja de LangeJoseph V Raimondo
Oct 28, 2018·Acta Parasitologica·Kaushik SatyaprakashSunil W Kolte

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