Clinical studies of mucin-producing cholangiocellular carcinoma: a study of 22 histopathology-proven cases

Annals of Surgery
M F ChenT C Chen

Abstract

We present the clinical features and outcomes of 22 surgically treated and histopathology-proven cases of mucin-producing cholangiocellular carcinoma (MPCCC). Cholangiocellular carcinoma (CCC) is an uncommon malignancy. Unlike hepatocellular carcinoma, it is difficult to set up a high-risk group, and a specific tumor marker has yet to be found. Chronic liver disease is usually not found to be associated with CCC. Information about patients with MPCCC is limited, and the frequency of MPCCC in all patients with CCC has not been reported. The clinical features of 22 surgically treated and histopathology-proven cases of MPCCC were reviewed, including morbidity, mortality, and follow-up results. Factors that may influence the outcomes were also analyzed. Clinical features and outcomes of 148 patients with non-mucin-producing cholangiocellular carcinoma (non-MPCCC) were also summarized for comparison. Of 170 cases of CCC, 22 (12.9%) were MPCCC. Imaging studies were important in the differential diagnosis of CCC. Operative findings (e.g., gross appearance of the liver, mucobilia found by common bile duct exploration, choledochoscopic findings, and frozen section) were useful in the diagnosis of MPCCC. Surgical procedures included comm...Continue Reading

References

Nov 1, 1989·Gastrointestinal Endoscopy·M F ChenT L Hwang
Sep 1, 1988·Radiology·T KokuboM Minami
Jun 1, 1987·Gastrointestinal Endoscopy·R P VenuJ Stone
Jan 1, 1987·The British Journal of Surgery·N S HadjisLeslie H Blumgart
Sep 1, 1972·Journal of Clinical Pathology·P J GallagherM J Mitchinson
Nov 1, 1974·American Journal of Surgery·J Sanguily, V O Calderin
Feb 1, 1972·Annals of Surgery·M Balasegaram
Feb 1, 1972·Annals of Surgery·T MakiT Matsushiro
Feb 1, 1972·Annals of Surgery·C C Wen, H C Lee
Dec 1, 1984·Journal of Clinical Gastroenterology·P H ChenH C Ko
Feb 1, 1982·The British Journal of Surgery·T K ChoiG B Ong
Jan 11, 1962·The New England Journal of Medicine·R B CATTELLF KAHN

Citations

Aug 4, 2009·Journal of Hepato-biliary-pancreatic Sciences·Masayuki OhtsukaMasaru Miyazaki
Feb 2, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Mee Joo KangSun-Whe Kim
Mar 17, 2019·International Journal of Molecular Sciences·Aldona Kasprzak, Agnieszka Adamek
Feb 24, 2000·The American Journal of Gastroenterology·T S YehM F Chen
Feb 8, 2005·Laboratory Investigation; a Journal of Technical Methods and Pathology·Y ZenYasuni Nakanuma
Oct 9, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Shuichiro UchiyamaKazuhiro Kondo
Mar 27, 2009·Journal of Hepato-biliary-pancreatic Surgery·Yoshitsugu NakanishiSatoshi Kondo
Jun 21, 2014·International Journal of Hepatology·Masayuki OhtsukaMasaru Miyazaki
Dec 18, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Y SudoYasuni Nakanuma
Dec 31, 1998·Journal of Gastroenterology and Hepatology·M F Chen
Mar 30, 2004·Laboratory Investigation; a Journal of Technical Methods and Pathology·Akira IshikawaYasuni Nakanuma
Jul 9, 2008·Scandinavian Journal of Gastroenterology·Yung-Kuan TsouYi-Yin Jan
Jan 20, 2004·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jae Hoon LimKyung Jin Nam
Aug 24, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Ta-Sen YehMiin-Fu Chen
Mar 5, 2008·Journal of Surgical Oncology·Kwang Yeol PaikDong Wook Choi
Aug 27, 2010·Surgery Today·Sheng-Dong WuJue Zhou
Mar 5, 2016·Surgical Case Reports·Gen TakahashiHideki Ohdan
Sep 2, 1999·Japanese Journal of Clinical Oncology·A SaiuraM Makuuchi
Dec 29, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K S SuhS W Kim
Feb 11, 2004·Cancer·Sang Soo LeeYoung Il Min
Jun 3, 2004·Annals of Surgical Oncology·Chun-Nan YehMiin-Fu Chen
Apr 7, 2009·Virchows Archiv : an International Journal of Pathology·Banu YamanMurat Kilic
Jun 30, 2016·Journal of Gastroenterology and Hepatology·Vor LuviraSupot Kamsa-Ard

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