Clinical studies of the effect of blood storage on patient outcomes

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
Darrell J Triulzi, Mark H Yazer

Abstract

It is indisputable that there are numerous biochemical, structural, inflammatory, and physiologic changes in stored red cells, sometimes referred to collectively as the "red cell storage lesion". It remains controversial however whether any of these changes have clinical relevance and actually impact the clinical outcomes in transfused patients. More than 25 published clinical studies have evaluated the effects of red blood cell storage on patient outcomes. The majority of studies are non-randomized observational studies with methodologic limitations described in this review. These studies do however provide equipoise to support the ethical conduct of the large, definitive randomized clinical trials which are now underway.

References

Oct 1, 1995·Critical Care Medicine·J C MarshallW J Sibbald
Jun 16, 1993·JAMA : the Journal of the American Medical Association·P E Marik, W J Sibbald
Jan 16, 1998·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·F R PurdyP M Merrick
Aug 8, 1998·The European Journal of Surgery = Acta Chirurgica·T H Edna, T Bjerkeset
Feb 12, 2000·American Journal of Surgery·G ZallenC C Silliman
Aug 10, 2001·Diseases of the Colon and Rectum·T MynsterUNKNOWN Danish RANX05 Colorectal Cancer Study Group
Dec 12, 2001·Critical Care : the Official Journal of the Critical Care Forum·C J FernandesE Knobel
Jun 5, 2002·The Journal of Trauma·Carl I SchulmanStephen M Cohn
Jun 7, 2002·Archives of Surgery·Patrick J OffnerChristopher C Silliman
Nov 19, 2002·The Journal of Trauma·Mary E KellerErwin Hirsch
Mar 27, 2003·Anesthesiology·Santiago R Leal-NovalJesús Loscertales
Apr 23, 2005·Anesthesia and Analgesia·Paul C HébertUNKNOWN Canadian Critical Care Trials Group
Jun 8, 2006·Vox Sanguinis·J R Hess
Jul 20, 2006·Critical Care Medicine·Robert W TaylorChristopher Veremakis
May 25, 2007·Critical Care Medicine·Yasser SakrDaniel De Backer
Mar 21, 2008·The New England Journal of Medicine·Colleen Gorman KochEugene H Blackstone
Apr 2, 2008·Thrombosis Research·Terry R KetchDavid C Sane
Apr 2, 2008·Critical Care Medicine·Santiago Ramón Leal-NovalFrancisco Murillo-Cabezas
Jul 22, 2008·The Annals of Thoracic Surgery·Cheng-Hon YapMichael Yii
Aug 6, 2008·Critical Care Medicine·Paul E Marik, Howard L Corwin
Aug 13, 2008·The Journal of Trauma·Jordan A WeinbergLoring W Rue
Dec 6, 2008·Transfusion Medicine Reviews·Dean FergussonRobin Walker
Jan 21, 2009·Vox Sanguinis·A B Zimrin, J R Hess
Jul 16, 2009·Transfusion·Marie E Steiner, Christopher Stowell
Sep 24, 2009·Critical Care : the Official Journal of the Critical Care Forum·Philip C SpinellaJohn B Holcomb

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Citations

Jan 10, 2014·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Keyvan Karkouti
Oct 9, 2014·Journal of Blood Transfusion·Lauren M McDanielMatthew D Neal
Sep 29, 2011·Archives of Internal Medicine·Mary A M RogersSanjay Saint
Jan 16, 2013·Annals of Intensive Care·Cécile AubronRinaldo Bellomo
Feb 14, 2013·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Banu AyhanUlku Aypar
Apr 9, 2015·The New England Journal of Medicine·Marie E SteinerChristopher P Stowell
Jan 18, 2016·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Matthew S KarafinJoshua J Field
Aug 19, 2010·American Journal of Clinical Pathology·Mark H Yazer, Darrell J Triulzi
Jul 27, 2010·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·M E SteinerC P Stowell
Jun 2, 2010·Clinics in Laboratory Medicine·Stewart Abbot
Dec 17, 2015·Revista brasileira de hematologia e hemoterapia·Lilian Castilho
Apr 19, 2011·Transfusion·Daniel B Kim-ShapiroMark T Gladwin
May 7, 2011·Transfusion·Jonathan H Waters, Paul M Ness
Oct 5, 2012·British Journal of Haematology·Stella T ChouAlexis A Thompson
Dec 3, 2014·Anaesthesia·D Orlov, K Karkouti
Mar 26, 2014·Transfusion·Michael TarasevJed B Gorlin
Jul 17, 2015·Transfusion·Jillian A PattersonJane B Ford
Dec 3, 2014·The Journal of Arthroplasty·Brian R HamlinTim J Levison
May 5, 2012·Seminars in Cardiothoracic and Vascular Anesthesia·Steven B Edelstein
Jul 15, 2015·The Cochrane Database of Systematic Reviews·Arturo J Martí-CarvajalBarbra S Peña-González
Dec 14, 2011·Hematology·Karina YazdanbakhshHui Zhong
Oct 18, 2016·Current Opinion in Hematology·Akshay ShahSimon J Stanworth
Nov 5, 2013·American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses·Michael T McEvoy, Aryeh Shander

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