Clinical studies on plasma fibronectin and factor XIII; with special reference to hyperlipoproteinemia

Clinica Chimica Acta; International Journal of Clinical Chemistry
M P CucuianuS Roman


When compared to age-matched normal weight normolipidemic control subjects, plasma factor XIII, plasma fibronectin and serum cholinesterase levels were found to be markedly decreased in patients with decompensated cirrhosis of the liver, not significantly changed in hyperlipoproteinemia type IIa (heterozygous subjects) and increased in hypertriglyceridemic subjects (type IIb and IV) as well as in hyperlipidemic nephrotic patients. A possible accelerated hepatic synthesis of certain plasma proteins including factor XIII and fibronectin in patients with the nephrotic syndrome as well as in endogenous hypertriglyceridemia is envisaged. It is also considered that mural thrombi, richer in factor XIII and fibronectin, would be more resistant to fibrinolysis and more readily attached to subendothelial structures.


Dec 8, 1972·Annals of the New York Academy of Sciences·F Duckert
Dec 8, 1972·Annals of the New York Academy of Sciences·K LakiJ Farrell
Sep 1, 1965·Immunochemistry·G ManciniJ F Heremans
Mar 1, 1983·Hoppe-Seyler's Zeitschrift für physiologische Chemie·H G KlingemannK Havemann
Feb 1, 1980·The Journal of Clinical Investigation·Y Sakata, N Aoki
Jan 1, 1981·Annals of the New York Academy of Sciences·K M BrinkhousT R Griggs
Feb 5, 1982·Clinica Chimica Acta; International Journal of Clinical Chemistry·M MatsudaA Matsuda
Jan 1, 1981·Nephron·K YoshiokaS Maki
Mar 5, 1981·Clinica Chimica Acta; International Journal of Clinical Chemistry·M P CucuianuI Missits
May 1, 1981·Journal of Clinical Pathology·N E StathakisE Tsianos


Jun 15, 1988·Klinische Wochenschrift·V de AngelisR Zuin
Jun 15, 1989·Clinica Chimica Acta; International Journal of Clinical Chemistry·K CsehL Romics
Jul 1, 1988·Atherosclerosis·M Cucuiano
Jun 1, 1991·Clinical Biochemistry·M Plebani, A Burlina

Related Concepts

Factor VIII Procoagulant Activity
Factor XIII A-Chain
Fibrosis, Liver
Nephrotic Syndrome
Plasma Factor VIII Complex

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.

© 2021 Meta ULC. All rights reserved