Clinical studies on plasma fibronectin and factor XIII; with special reference to hyperlipoproteinemia

Clinica Chimica Acta; International Journal of Clinical Chemistry
M P CucuianuS Roman

Abstract

When compared to age-matched normal weight normolipidemic control subjects, plasma factor XIII, plasma fibronectin and serum cholinesterase levels were found to be markedly decreased in patients with decompensated cirrhosis of the liver, not significantly changed in hyperlipoproteinemia type IIa (heterozygous subjects) and increased in hypertriglyceridemic subjects (type IIb and IV) as well as in hyperlipidemic nephrotic patients. A possible accelerated hepatic synthesis of certain plasma proteins including factor XIII and fibronectin in patients with the nephrotic syndrome as well as in endogenous hypertriglyceridemia is envisaged. It is also considered that mural thrombi, richer in factor XIII and fibronectin, would be more resistant to fibrinolysis and more readily attached to subendothelial structures.

References

Dec 8, 1972·Annals of the New York Academy of Sciences·F Duckert
Dec 8, 1972·Annals of the New York Academy of Sciences·K LakiJ Farrell
Sep 1, 1965·Immunochemistry·G ManciniJ F Heremans
Mar 1, 1983·Hoppe-Seyler's Zeitschrift für physiologische Chemie·H G KlingemannK Havemann
Feb 1, 1980·The Journal of Clinical Investigation·Y Sakata, N Aoki
Jan 1, 1981·Annals of the New York Academy of Sciences·K M BrinkhousT R Griggs
Feb 5, 1982·Clinica Chimica Acta; International Journal of Clinical Chemistry·M MatsudaA Matsuda
Jan 1, 1981·Nephron·K YoshiokaS Maki
Mar 5, 1981·Clinica Chimica Acta; International Journal of Clinical Chemistry·M P CucuianuI Missits
May 1, 1981·Journal of Clinical Pathology·N E StathakisE Tsianos

Citations

Jun 15, 1988·Klinische Wochenschrift·V de AngelisR Zuin
Jun 15, 1989·Clinica Chimica Acta; International Journal of Clinical Chemistry·K CsehL Romics
Jul 1, 1988·Atherosclerosis·M Cucuiano
Jun 1, 1991·Clinical Biochemistry·M Plebani, A Burlina

Related Concepts

Antigens
Factor VIII Procoagulant Activity
Factor XIII A-Chain
Fibronectins
Hyperlipoproteinemias
Fibrosis, Liver
Nephrotic Syndrome
Plasma Factor VIII Complex

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