PMID: 6407291Jan 1, 1983Paper

Clinical studies on the protective effects of Ketotifen and Intal in atopic asthmatic patients

Allergologia et immunopathologia
B RománskiT Wilewska-Klubo

Abstract

The study was undertaken to compare the protective action of HC 20-511 (Ketotifen) and disodium cromoglycate (Intal) in patients with the atopic form of asthma. A total of 50 asthmatics, 26 men and 24 women, aged 14 to 45 were examined by a double-blind controlled method. In the group examined, both Ketotifen and Intal were administered in 25 patients during 12 weeks. Ketotifen was highly effective in 14 patients (56.0 percent) while the results of treatment by Intal were highly effective in 19 patients (76.0 per cent). The tolerance to Ketotifen and Intal was excellent or good, respectively in 88 per cent and 100 per cent of treated persons. In the authors opinion, Ketotifen and Intal have a valuable protective effect in atopic asthma cases, but both are less effective in patients with recurrent infections of the respiratory tract.

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