Clinical study of cutaneous drug eruptions in 200 patients

Indian Journal of Dermatology, Venereology and Leprology
M Patel Raksha, Y S Marfatia

Abstract

Two hundred patients (112 males and 88 females) with cutaneous drug eruption were studied. The aim was to recognize the offending drug, to evaluate mortality and morbidity, educate the patient and avoid self-administration and readministration of drugs. Fixed drug eruption was the commonest reaction, seen in 61 patients; other reactions being urticaria and angioedema,morbilliform rash in 37, pruritus in 25, Stevens Johnson Syndrome (SJS) in 6, purpura in 6, exfoliative dermatitis in 5,photosensitivity in 5, toxic epidermal necrolysis in 2, acneiform eruption in 3, erythema multiforme in 2. Maximum patients belonged to the age group 41-50, followed by 21-30 and 31-40 years. The youngest was 1 year old and the oldest was 80 years old. Period of development of lesion after intake of drug varied from 1 day to 45 days. Cotrimoxazole was the commonest drug, in 26 cases; followed by Ibuprofen in 20 cases.

Citations

Oct 4, 2011·Indian Journal of Dermatology·Ashish AggarwalDinesh Dutt Sharma
Jan 12, 2011·Indian Journal of Dermatology, Venereology and Leprology·Sanjiv Grover
Jun 19, 2012·Indian Journal of Dermatology·Fatma Akpinar, Emine Dervis
May 14, 2014·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·K Maleki, E Weisshaar
Nov 10, 2015·Annales de dermatologie et de vénéréologie·L Valeyrie-AllanoreUNKNOWN sous l’égide du groupe toxidermie de la Société française de dermatologie (FISARD)
Sep 29, 2011·Journal of Clinical Pharmacology·Nadia Ben FredjNaceur Abderrazek Boughattas
Feb 20, 2015·Drugs & Aging·Rodrigo Valdes-RodriguezGil Yosipovitch
Jul 4, 2008·Current Opinion in Allergy and Clinical Immunology·Sidonie Nelly LavergneDean John Naisbitt
Aug 8, 2009·The British Journal of Dermatology·A B Alexandroff, R A C Graham-Brown
Sep 16, 2011·The British Journal of Dermatology·L M HeinzerlingM D Anliker
Jul 14, 2010·International Journal of Dermatology·Wen Yi DingSiew Eng Choon
Apr 5, 2013·Dermatologic Therapy·Lilit GaribyanSarina B Elmariah
Aug 28, 2020·Dermatologic Therapy·Eray YıldızGökhan Aytekin
Apr 22, 2015·Clinical Biochemistry·Manuela G NeumanRadu M Nanau

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Indian Journal of Dermatology, Venereology and Leprology
S SehgalS D Shenoi
Dermatology : International Journal for Clinical and Investigative Dermatology
Christa PrinsLars E French
Allergology International : Official Journal of the Japanese Society of Allergology
Yumiko YamaneZenro Ikezawa
© 2021 Meta ULC. All rights reserved