Clinical Study on the Screening of Lower Extremity Deep Venous Thrombosis by D-Dimer Combined with RAPT Score Among Orthopedic Trauma Patients.

Indian Journal of Orthopaedics
Xin ZhaoXiguang Sang

Abstract

Among the causes of mortality in patients with lower extremity fracture following surgery, lower extremity deep venous thrombosis (DVT) is a leading one. To lower the morbidity and mortality, early screening and preventive anticoagulation therapy are essential in clinical study. Common screening methods, including risk prediction tools, imaging tests and D-dimer test, had various drawbacks. The study aimed to establish a new method, that is, D-dimer combined with Risk Assessment and Predictor Tool (RAPT) score, for screening the lower extremity DVT among patients with lower extremity fracture and evaluate its clinical value. The RAPT score, plasma D-dimer and lower extremity venous ultrasonography examination reports were collected from Department of Emergency Surgery & Orthopaedic Surgery from July 2019 to December 2019, and the data were analyzed retrospectively. Regarding the lower extremity venous ultrasonography examination report as the "gold standard" to determine whether DVT exists, the sensitivity, specificity and area under the curve (AUC) of RAPT score alone, plasma D-dimer alone and combination of them in screening lower extremity DVT were analyzed and evaluated. 197 patients were enrolled in the study. There were s...Continue Reading

References

Jan 1, 1997·The Journal of Trauma·L J GreenfieldJ Cho
Apr 12, 2003·The American Journal of Medicine·Daniel J BrotmanThomas S Kickler
Mar 29, 2006·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Motonobu TeraoToru Sato
Dec 13, 2006·Journal of Thrombosis and Haemostasis : JTH·M Di NisioP M M Bossuyt
Apr 19, 2008·Journal of Thrombosis and Haemostasis : JTH·M RighiniH Bounameaux
Apr 18, 2013·American Journal of Surgery·Damian HegstedKelly Dean Gubler
Feb 19, 2015·International Orthopaedics·Philipp LichteUNKNOWN Trauma Register DGU
Mar 24, 2015·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Takahiro NiikuraMasahiro Kurosaka
Sep 18, 2016·Advances in Experimental Medicine and Biology·Vivak HansraniCharles McCollum
Feb 20, 2017·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Alvin R WuNicos Labropoulos
Jan 9, 2018·Annals of Internal Medicine·Philip S WellsMelissa Anne Forgie
Jan 30, 2019·The Journal of Surgical Research·Grace E MartinMichael D Goodman
Mar 20, 2019·Thrombosis Research·Dawn SwanJecko Thachil
Jan 12, 2020·Journal of Thrombosis and Haemostasis : JTH·Marc BlondonHelia Robert-Ebadi
May 25, 2020·Thrombosis Research·Fridtjof B RindeSigrid K Brækkan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.