Clinical trials: new opportunities.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Sandra B ChapmanChristopher H van Dyck

Abstract

Human cognitive aging has been too long neglected and underappreciated for its critical importance to quality of life in old age. The articles in this session present novel approaches to improving cognitive function in normal aging persons with drugs and interventions that are based on findings in epidemiology, studies in aged animals, and in vitro research. In addition, since aging is the primary risk factor for Alzheimer's disease, these studies also have implications as interventions for prevention and treatment. As a field of research, new knowledge regarding the causes and mechanisms of cognitive aging are ripe for translation into human studies, with the application of this knowledge leading the development of interventions and therapeutics for the prevention of cognitive decline in old age and Alzheimer's disease.

References

Nov 1, 1996·Pharmacology, Biochemistry, and Behavior·P RämäS Carlson
Sep 26, 1997·Alzheimer Disease and Associated Disorders·J J Harding
Jan 14, 1999·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·P JäkäläP Riekkinen
Apr 8, 1999·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·P JäkäläP Riekkinen
Nov 13, 2002·JAMA : the Journal of the American Medical Association·Karlene BallUNKNOWN Advanced Cognitive Training for Independent and Vital Elderly Study Group
Dec 10, 2002·Neuroscience and Biobehavioral Reviews·Alan Peters
Feb 14, 2004·Journal of the American Geriatrics Society·Donald R RoyallMarsha J Polk
Nov 16, 2004·Ageing Research Reviews·Lawrence J WhalleyJohn M Starr
Jul 22, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Iain A WilsonHeikki Tanila
Aug 4, 2005·Psychopharmacology·Ulrich MüllerTrevor W Robbins
Jan 6, 2006·Aging Clinical and Experimental Research·Angelo ScuteriSimona Giampaoli
Dec 15, 2006·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Stanley J ColcombeArthur F Kramer
Aug 3, 2007·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·George W RebokJessica B S Langbaum
Mar 22, 2008·Science·Arnold BakkerCraig E L Stark
Dec 20, 2008·Journal of Alzheimer's Disease : JAD·Carl W Cotman, Elizabeth Head
Jan 6, 2009·Hippocampus·Kirk I EricksonArthur F Kramer
May 1, 2009·Learning & Memory·Chelsea K TonerPaul E Gilbert
Sep 24, 2009·JAMA : the Journal of the American Medical Association·Farrell J Lloyd, Valerie F Reyna
Oct 31, 2009·Neuropsychology Review·Cindy LustigPatricia A Reuter-Lorenz
Dec 25, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Ming Teng KohMichela Gallagher
Mar 20, 2010·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·UNKNOWN Alzheimer's Association
May 8, 2010·Neurobiology of Aging·Margaret FahnestockCarl W Cotman
Apr 1, 1991·Applied Optics·P CorrederaA Pons
Oct 22, 2010·International Journal of Geriatric Psychiatry·Raksha AnandJohn Hart
Jul 29, 2011·Nature·Min WangAmy F T Arnsten

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Citations

Oct 19, 2013·Rejuvenation Research·Brent J SmallPaula C Bickford
Jun 14, 2015·Trends in Molecular Medicine·Joseph A McQuailJennifer L Bizon

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