PMID: 9552517Dec 1, 1996Paper

Clinical trials on intracoronary stenting

Seminars in Interventional Cardiology : SIIC
P P de JaegereP W Serruys

Abstract

The stent is currently taking the lead in the treatment of obstructive coronary artery disease. The interest in this device is not only reflected by the relative number of patients referred for angioplasty and treated with a stent but also by the large number of clinical trials. These can be divided into trials assessing the safety and feasibility of the implantation of second generation or new stents, studies assessing novel treatment strategies and randomized clinical trials. With respect to the latter, they all compare stent implantation with balloon angioplasty. Of major importance will be the comparison of stent implantation with surgical revascularization of obstructive coronary artery disease. The increasing number of therapeutic options, however, confront the physician with the difficult choice and responsibility of selecting the most appropriate treatment. Therefore, systematic and objective evaluation of the available therapeutic approaches by means of appropriately designed trials is imperative. The purpose of this paper is to summarize and to put into perspective the various studies on intracoronary stenting. Distinction is made between observational studies testing a device or evaluating a new concept in intracoron...Continue Reading

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