Clinical updates in hair

Dermatologic Clinics
M E Sawaya

Abstract

It is now known that there are major differences in the systemic and cellular mechanisms that mediate hair loss in women versus men. The severity or degree of hair loss in women with androgenetic alopecia is usually much less than in men. It is usually assumed that the hormonal basis for androgenetic alopecia in women is the same as in men; that is, the same target tissue-active androgens, testosterone and dihydrotestosterone, are being produced systemically to aggravate scalp hair follicles, resulting in hair loss. This article reviews some of the latest findings in androgenetic alopecia for both men and women, along with new and old treatments and drugs, doses, and effectiveness. Research findings indicate that levels of androgen-metabolizing enzymes and receptors differ in the scalps of women versus men, which may be important in formulating more effective hair growth treatments in the future.

References

Sep 5, 1992·Lancet·B J Kidwai, M George
Sep 1, 1992·Archives of Dermatology·W J Cunliffe, W W Bottomley
Sep 1, 1992·The British Journal of Dermatology·C JaworskyG F Murphy
Nov 1, 1992·International Journal of Dermatology·D A Whiting, C Jacobson
Jun 1, 1992·The Journal of Investigative Dermatology·M E Sawaya
Jun 1, 1992·Journal of the American Academy of Dermatology·T F Cash
Sep 27, 1990·The New England Journal of Medicine·S F SiegelP A Lee
Sep 27, 1990·The New England Journal of Medicine·D A Ehrmann, R L Rosenfield
Sep 1, 1990·Journal of the American Academy of Dermatology·L CusanF Labrie
Aug 1, 1988·The Journal of Investigative Dermatology·M E SawayaS L Hsia
Dec 1, 1974·The Journal of Clinical Endocrinology and Metabolism·H U Schweikert, J D Wilson
Jan 1, 1983·Cleveland Clinic Quarterly·J M KasickM K Gupta
Jan 1, 1982·Endocrine Reviews·W W GrodyB W O'Malley
Mar 5, 1982·JAMA : the Journal of the American Medical Association·D C CummingS S Yen
Dec 1, 1981·International Journal of Dermatology·R P Dawber
Oct 30, 1980·The New England Journal of Medicine·R A VigerskyC E Smith
Jan 1, 1964·Archives of Dermatology·M A SMITH, R S WELLS

❮ Previous
Next ❯

Citations

Apr 1, 2000·Clinics in Dermatology·B TüzünR Wolf
Jun 3, 1999·Endocrinology and Metabolism Clinics of North America·R S Rittmaster
Aug 12, 1999·The New England Journal of Medicine·R Paus, G Cotsarelis
Sep 3, 2013·Journal of Cosmetic Dermatology·Nattaya Lourith, Mayuree Kanlayavattanakul
Dec 31, 1997·Dermatologic Clinics·D B Stough, J E Miner
May 12, 2004·Facial Plastic Surgery Clinics of North America·Robert S Haber
Nov 12, 2005·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Franziska Conrad, Ralf Paus
Feb 9, 2000·American Journal of Physiology. Endocrinology and Metabolism·S ChandaR C Smart
Apr 1, 2000·Clinics in Dermatology·M E Sawaya, J Shapiro
Jan 8, 2000·Dermatologic Clinics·M E Sawaya, J Shapiro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.