Clinical use of 4D flow MRI for quantification of aortic regurgitation

Open Heart
Ana AlvarezJose Ángel Cabrera

Abstract

The main objective of the present study was to compare the use of four-dimensional (4D) flow MRI with the habitual sequence (two-dimensional phase-contrast (2DPC) MRI) for the assessment of aortic regurgitation (AR) in the clinical routine. This was a retrospective, observational cohort study of patients with varying grades of AR. For the purposes of the present study, we selected all the cases with a regurgitant fraction (RF)>5% as determined by 2DPC MRI (n=34). In all cases, both sequences (2DPC and 4D flow MRI) were acquired in a single session to ensure comparability. We compared the results of the two techniques by evaluating forward flow, regurgitant flow and regurgitation fraction. Then, the patients were divided into subgroups to determine if these factors had any influence on the measurements: aortic diameter (≤ vs >38 mm), valve anatomy (tricuspid vs bicuspid/quadricuspid), stenosis (gradient ≥15 vs <15) and region of interest location (aortic valve vs sinotubular junction). No statistically significant differences were observed between the two techniques with Pearson's correlation coefficients (r) of forward flow (r=0.826/p value<0001), regurgitant flow (r=0.866/p value<0001) and RF (r=0.761/p value<0001). The findin...Continue Reading

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Citations

Jul 20, 2021·Heart Failure Reviews·Carmen CioncaTeodora Mocan
Aug 21, 2021·Journal of Magnetic Resonance Imaging : JMRI·Ciara M DoyleMalenka M Bissell

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Methods Mentioned

BETA
imaging technique

Software Mentioned

SPSS
CardiacVX Advantage Workstation
Arterys

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