Clinical use of combined positron emission tomography and computed tomography in thymoma recurrence

Interactive Cardiovascular and Thoracic Surgery
Hatem Y El-BawabKhaled M Alkattan

Abstract

The aim of this study is to evaluate the efficacy of hybrid fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) for surveillance and follow-up of thymoma patients to detect recurrent disease. A retrospective chart review was performed on 37 thymoma patients who underwent FDG-PET/CT-scans during postoperative follow-up. The following information was obtained: clinical indication for FDG-PET/CT, the results of the FDG-PET/CT, particularly with regard to the additional diagnostic imaging information, the localization of the disease and subsequent clinical patient management. A total of 51 CT-scans were performed on 37 patients providing sensitivity and specificity for thymoma recurrence of 71% and 85%, respectively. Forty-five FDG-PET/CT-scans were performed on the same group of patients with an overall sensitivity and specificity of 82% and 95%, respectively. Notably, FDG-PET/CT sensitivity when employed for diagnosis of thymoma recurrence in the anterior mediastinum has reached 100% (CT has shown only 55% sensitivity for the detection of anterior mediastinal thymoma recurrence). Our preliminary study demonstrates that during follow-up after thymoma excision, FDG-PET/CT is superior to comp...Continue Reading

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Citations

Jun 9, 2015·PET Clinics·Mie Holm Vilstrup, Drew A Torigian
Nov 24, 2011·Thoracic Surgery Clinics·Paul M ClaiborneAra A Vaporciyan
Nov 30, 2010·Current Problems in Cancer·Jeffrey A Forquer
Aug 21, 2013·General Thoracic and Cardiovascular Surgery·Hironori IshibashiKenichi Okubo
Sep 2, 2016·Journal of Cardiothoracic Surgery·Taobo LuoXinming Zhou
Dec 20, 2012·Journal of Thoracic Imaging·Thomas C KweeAbass Alavi
May 8, 2021·Journal of the American College of Radiology : JACR·UNKNOWN Expert Panel on Thoracic ImagingJeffrey P Kanne

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