Clinical usefulness of right ventricular 3D area strain in the assessment of treatment effects of balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension: comparison with 2D feature-tracking MRI

European Radiology
Masateru KawakuboHiroshi Honda

Abstract

To evaluate the usefulness of right ventricular (RV) area strain analysis via cardiac MRI (CMRI) as a tool for assessing the treatment effects of balloon pulmonary angioplasty (BPA) in inoperable chronic thromboembolic pulmonary hypertension (CTEPH), RV area strain was compared to two-dimensional (2D) strain with feature-tracking MRI (FTMRI) before and after BPA. We retrospectively analyzed 21 CTEPH patients who underwent BPA. End-systolic global area strain (GAS), longitudinal strain (LS), circumferential strain (CS), and radial strain (RS) were measured before and after BPA. Changes in GAS and RV ejection fraction (RVEF) values after BPA were defined as ΔGAS and ΔRVEF. Receiver operating characteristic (ROC) analyses were performed to determine the optimal cutoff of the strain at after BPA for detection of improved patients with decreased mean pulmonary artery pressure (mPAP) less than 30 mmHg and increased RVEF more than 50%. ROC analysis revealed the optimal cutoffs of strains (GAS, LS, CS, and RS) for identifying improved patients with mPAP < 30 mmHg (cutoff (%) = - 41.2, - 13.8, - 16.7, and 14.4: area under the curve, 0.75, 0.56, 0.65, and 0.75) and patients with RVEF > 50% (cutoff (%) = - 37.2, - 29.5, - 2.9, and 14.4: a...Continue Reading

References

Jan 10, 2006·American Journal of Physiology. Heart and Circulatory Physiology·H Alex LeatherPatrick F Wouters
Jun 22, 2010·Echocardiography·Angel López-CandalesMaria Dolores Candales
Feb 23, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Sebastiaan A KleijnOtto Kamp
Mar 5, 2011·Journal of Visualized Experiments : JoVE·Kan N HorWojciech Mazur
Sep 24, 2011·Journal of the American College of Cardiology·John Gorcsan, Hidekazu Tanaka
Nov 30, 2012·Circulation. Cardiovascular Interventions·Hiroki MizoguchiHiromi Matsubara
Aug 21, 2013·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Victor Chien-Chia WuYutaka Otsuji
Mar 15, 2014·The European Respiratory Journal·Shigefumi FukuiNorifumi Nakanishi
Aug 6, 2014·Circulation·Irene Marthe Lang, Michael Madani
Dec 6, 2014·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Andreas RolfChristian W Hamm
Sep 20, 2015·The International Journal of Cardiovascular Imaging·Masateru KawakuboJunji Morishita
Mar 25, 2016·Circulation. Cardiovascular Imaging·Andreas SchusterShelby Kutty
Aug 27, 2016·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Gianni PedrizzettiEike Nagel
Mar 2, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Kenshi HayashiUNKNOWN Hokuriku-Plus AF Registry Investigators

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Citations

May 3, 2020·European Heart Journal Cardiovascular Imaging·Yuzo YamasakiHidetake Yabuuchi
Jun 13, 2021·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Masateru KawakuboShuji Sakai
Aug 24, 2021·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Marc de PerrotWilliam R Auger

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