Clinical utility of chest radiography for severe COVID-19

Quantitative Imaging in Medicine and Surgery
Terrence Chi Hong HuiCher Heng Tan

Abstract

Chest radiography (CXR) is performed more widely and readily than CT for the management of coronavirus disease (COVID-19), but there remains little data on its clinical utility. This study aims to assess the diagnostic performance of CXR, with emphasis on its predictive value, for severe COVID-19 disease. A retrospective cohort study was conducted, 358 chest radiographs were performed on 109 COVID-19 patients (median age 44.4 years, 58 males and 30 with comorbidities) admitted between 22 January 2020 and 15 March 2020. Each CXR was reviewed and scored by three radiologists in consensus using a 72-point COVID-19 Radiographic Score (CRS). Disease severity was determined by the need for supplemental oxygen and mechanical ventilation. Patients who needed supplemental oxygen (n=19, 17.4%) were significantly older (P<0.001) and significantly more of them had co-morbidities (P=0.011). They also had higher C-reactive protein (CRP) (P<0.001), higher lactate dehydrogenase (LDH) (P<0.001), lower lymphocyte count (P<0.001) and lower hemoglobin (Hb) (P=0.001). Their initial (CRSinitial) and maximal CRS (CRSmax) were higher (P<0.001). Adjusting for age and baseline hemoglobin, the AUROC of CRSmax (0.983) was as high as CRPmax (0.987) and hig...Continue Reading

Citations

Jan 15, 2021·PloS One·Sean Wei Xiang OngDavid Chien Lye
Jan 5, 2021·European Journal of Radiology Open·Yongxing YunQingxian Cai
Feb 10, 2021·Radiology·Jeffrey P KanneNicola Sverzellati
Dec 16, 2020·European Radiology Experimental·Cristian Giuseppe MonacoFrancesco Sardanelli
Jun 18, 2021·International Journal of General Medicine·Rosy SetiawatiImran Harsam Kamal
Jul 11, 2021·Radiología·A Adarve CastroD Domínguez Pinos

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