Clinical utility of mental state screening as a predictor of intellectual outcomes 6 months after diagnosis of type 1 diabetes

Pediatric Diabetes
Caroline NadebaumDiabetic Ketoacidosis and Brain Injury Study Group

Abstract

Screening tests of basic cognitive status or 'mental state' have been shown to predict mortality and functional outcomes in adults. This study examined the relationship between mental state and outcomes in children with type 1 diabetes. We aimed to determine whether mental state at diagnosis predicts longer term cognitive function of children with a new diagnosis of type 1 diabetes. Mental state of 87 patients presenting with newly diagnosed type 1 diabetes was assessed using the School-Years Screening Test for the Evaluation of Mental Status. Cognitive abilities were assessed 1 wk and 6 months postdiagnosis using standardized tests of attention, memory, and intelligence. Thirty-seven children (42.5%) had reduced mental state at diagnosis. Children with impaired mental state had poorer attention and memory in the week following diagnosis, and, after controlling for possible confounding factors, significantly lower IQ at 6 months compared to those with unimpaired mental state (p < 0.05). Cognition is impaired acutely in a significant number of children presenting with newly diagnosed type 1 diabetes. Mental state screening is an effective method of identifying children at risk of ongoing cognitive difficulties in the days and mo...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Dec 6, 2003·Pediatric Diabetes·Andreas NeuUNKNOWN DIARY Group Baden-Wuerttemberg
Feb 7, 2006·Diabetes Research and Clinical Practice·Stephanie T ChungMichael S Boyne
Feb 2, 2008·IEEE Transactions on Neural Networks·Chengjun Liu, H Wechsler
Jan 20, 2009·Diabetes Care·Elisabeth A NorthamFergus J Cameron

❮ Previous
Next ❯

Citations

Feb 19, 2013·Ageing Research Reviews·Jim R FadelLawrence P Reagan
Apr 17, 2015·Archives of Disease in Childhood·Soulmaz Fazeli FarsaniAukje K Mantel-Teeuwisse
Jan 7, 2017·Journal of Child Neurology·Sherifa HamedTahra Sherief
Jan 1, 2015·Expert Review of Endocrinology & Metabolism·Nelia P SteynAndre-Pascal Kengne
Dec 24, 2018·Diabetes Care·Tandy AyeUNKNOWN Diabetes Research in Children Network (DirecNet) Study Group

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diabetes & Tolerance

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.