Clinical utility of ocular residual astigmatism and topographic disparity vector indexes in subclinical and clinical keratoconus

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
David PiñeroAlberto Artola

Abstract

We aimed to characterize the distribution of the vector parameters ocular residual astigmatism (ORA) and topography disparity (TD) in a sample of clinical and subclinical keratoconus eyes, and to evaluate their diagnostic value to discriminate between these conditions and healthy corneas. This study comprised a total of 43 keratoconic eyes (27 patients, 17-73 years) (keratoconus group), 11 subclinical keratoconus eyes (eight patients, 11-54 years) (subclinical keratoconus group) and 101 healthy eyes (101 patients, 15-64 years) (control group). In all cases, a complete corneal analysis was performed using a Scheimpflug photography-based topography system. Anterior corneal topographic data was imported from it to the iASSORT software (ASSORT Pty. Ltd), which allowed the calculation of ORA and TD. Mean magnitude of the ORA was 3.23 ± 2.38, 1.16 ± 0.50 and 0.79 ± 0.43 D in the keratoconus, subclinical keratoconus and control groups, respectively (p < 0.001). Mean magnitude of the TD was 9.04 ± 8.08, 2.69 ± 2.42 and 0.89 ± 0.50 D in the keratoconus, subclinical keratoconus and control groups, respectively (p < 0.001). Good diagnostic performance of ORA (cutoff point: 1.21 D, sensitivity 83.7 %, specificity 87.1 %) and TD (cutoff poi...Continue Reading

References

Feb 1, 1996·Acta Ophthalmologica Scandinavica·M C DunneD A Barnes
Jan 1, 1997·Journal of Cataract and Refractive Surgery·N A Alpins
Mar 11, 1998·Survey of Ophthalmology·Y S Rabinowitz
Feb 13, 2001·Journal of Cataract and Refractive Surgery·N Alpins
Dec 2, 2005·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Marine Gobbe, Michel Guillon
Nov 4, 2006·Journal of Cataract and Refractive Surgery·Renato AmbrósioLuis Guillermo Coca Velarde
Mar 26, 2008·Journal of Cataract and Refractive Surgery·Mohammad-Reza NilforoushanRobert Latkany
May 13, 2008·Journal of Cataract and Refractive Surgery·Zuzana SchlegelDamien Gatinel
Nov 13, 2009·Investigative Ophthalmology & Visual Science·David P PiñeroRamón Jiménez
Feb 9, 2010·Ophthalmology·Bruno M FontesWalton Nosé
Oct 15, 2010·Arquivos brasileiros de oftalmologia·Bruno Machado FontesWalton Nosé
Feb 22, 2011·Journal of Cataract and Refractive Surgery·Jorge L AlióAntonio Uceda-Montanes
May 21, 2011·Journal of Cataract and Refractive Surgery·Ömür Ö UçakhanAyfer Kanpolat
Aug 4, 2011·Investigative Ophthalmology & Visual Science·Colm McAlindenKonrad Pesudovs
Oct 8, 2011·Journal of Cataract and Refractive Surgery·David TouboulCynthia J Roberts
Aug 7, 2012·European Journal of Ophthalmology·Vassilios KozobolisGeorgios Labiris
Sep 25, 2012·Journal of Cataract and Refractive Surgery·Nienke VisserRudy M M A Nuijts
Nov 10, 2012·International Ophthalmology·Seyed Mahdi Ahmadi HosseiniChandramalar T Santhirathelagan
Dec 1, 2012·Journal of Cataract and Refractive Surgery·David P PiñeroAlberto Lopez-Miguel
Jan 22, 2013·European Journal of Ophthalmology·Mohammad Reza JafarinasabHossein Hasanpour
Aug 6, 2013·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·David P PiñeroAlberto Artola

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Citations

Apr 14, 2016·American Journal of Ophthalmology·Mohammad NaderanParviz Zarrinbakhsh
Apr 9, 2020·Journal of Refractive Surgery·Maria A HenriquezLuis Izquierdo

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