PMID: 11933571Apr 6, 2002Paper

Clinical utility of the band count

Clinics in Laboratory Medicine
P Joanne Cornbleet

Abstract

Enumeration of band neutrophils has a long clinical tradition as a diagnostic test for bacterial infection. Yet, the band count is a nonspecific, inaccurate, and imprecise laboratory test. Review of the literature provides little support for the clinical utility of the band count in patients greater than 3 months of age. The white blood cell count and the automated absolute neutrophil count are better diagnostic tests for adults and most children. Absolute numbers of bands are required for the Rochester criteria, a diagnostic algorithm for acutely ill, febrile children less than 3 months of age. No studies, however, assess the independent contribution of bands to the performance of the algorithm, or the use of the automated total neutrophil count as a replacement for the band count. Band counts also are required to calculate an immature to total neutrophil ratio (I:T ratio), an index widely used to aid in the diagnosis of neonatal sepsis. Studies, however, show a wide range of sensitivity and specificity for the I:T ratio, indicating variable performance. In the near future, rapid analysis of inflammatory factors, adhesion molecules, cytokines, neutrophil surface antigens, or even bacterial DNA may be superior alternative tests...Continue Reading

References

Jan 1, 1992·Journal of Perinatal Medicine·T KredietG van Stekelenburg
Jan 1, 1992·Scandinavian Journal of Infectious Diseases·Z HalpernY Levo
Aug 1, 1990·Clinical Pediatrics·C W BronerJ M Sherman
Dec 1, 1990·The Pediatric Infectious Disease Journal·D N Greenberg, B A Yoder
Jun 1, 1990·Archives of Internal Medicine·L LeiboviciA J Wysenbeek
Jun 1, 1990·The Pediatric Infectious Disease Journal·C A McCarthyH Meyer
Jun 1, 1989·Journal of the American Geriatrics Society·M WassermanT T Yoshikawa
Jan 1, 1987·The American Journal of Emergency Medicine·C M SlovisR P Bain
Aug 1, 1987·Southern Medical Journal·J C KingP F Wright
May 1, 1988·The Journal of Pediatrics·R L RodwellD I Tudehope
Jun 1, 1988·Archives of Disease in Childhood·P KiteP Congdon
Mar 1, 1986·Annals of Emergency Medicine·G P Young
May 1, 1987·The Pediatric Infectious Disease Journal·T B ColeG R Buchanan
Apr 1, 1987·Archives of Internal Medicine·J W MellorsS M Horwitz
Dec 1, 1985·Annals of Emergency Medicine·P J CrockerW McCombs
Jan 1, 1982·Infection·D FriedA Hanukoglu
Jun 1, 1982·American Journal of Diseases of Children·J S Lobel, K E Bove
Sep 1, 1982·Acta paediatrica Scandinavica·N H Rasmussen, L N Rasmussen
Mar 1, 1995·Journal of the American Geriatrics Society·P PfitzenmeyerJ P Michel
Oct 1, 1994·The Journal of Pediatrics·R L SchelonkaJ Butler
May 1, 1994·The Pediatric Infectious Disease Journal·O DaSilva, O Hammerberg
May 1, 1993·The Pediatric Infectious Disease Journal·R L RodwellP H Gray
Mar 1, 1993·World Journal of Surgery·H JohnM Kelemen
Oct 1, 1995·Pediatric Emergency Care·R Bachur, G L Caputo
Jan 1, 1997·The Pediatric Infectious Disease Journal·C H ChiuM J Bullard
Apr 16, 1998·The Pediatric Infectious Disease Journal·C H Chiu, T Y Lin
Jun 13, 1998·Annals of Emergency Medicine·N KuppermannD M Jaffe
Jul 17, 1998·Archives of Pediatrics & Adolescent Medicine·G M Lee, M B Harper
Mar 23, 1999·Archives of Pediatrics & Adolescent Medicine·N Kuppermann, E A Walton
Jan 12, 2000·Pediatric Clinics of North America·N Kuppermann
Nov 4, 2000·Pediatrics·D J IsaacmanM Harper
May 19, 2001·Blood Cells, Molecules & Diseases·E Beutler

❮ Previous
Next ❯

Citations

Mar 4, 2005·American Journal of Clinical Pathology·Kelly G NigroLinda M Sandhaus
May 19, 2004·Clinical Chemistry and Laboratory Medicine : CCLM·J J M L Hoffmann
May 19, 2004·Clinical Chemistry and Laboratory Medicine : CCLM·Wim van der MeerMarinus H de Keijzer
Aug 1, 2009·Clinical Chemistry and Laboratory Medicine : CCLM·Johannes J M L Hoffmann
Sep 26, 2009·Clinical Chemistry and Laboratory Medicine : CCLM·Paul FroomMira Barak
Feb 27, 2010·Clinical Chemistry and Laboratory Medicine : CCLM·Bárbara L dos Anjos, Helena Z W Grotto
Sep 23, 2011·Clinical Chemistry and Laboratory Medicine : CCLM·Larry H Bernstein, James Rucinski
Jul 19, 2005·Laboratory Hematology : Official Publication of the International Society for Laboratory Hematology·Bruce H Davis, Nancy C Bigelow
Mar 14, 2007·Laboratory Hematology : Official Publication of the International Society for Laboratory Hematology·Robert BagdasaryanDongsheng Xu
Dec 24, 2015·Journal of Biophotonics·Ethan Schonbrun, Giuseppe Di Caprio
Jun 20, 2014·Critical Care Medicine·Estelle GuérinBruno François
Jan 18, 2006·European Journal of Haematology·Wim van der MeerHans Willems
Feb 23, 2011·International Journal of Laboratory Hematology·D-H ParkK Han
Jul 26, 2011·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Gert-Jan van de GeijnTjin Njo
Sep 17, 2013·Journal of Clinical Laboratory Analysis·Nau IshimineTakehisa Matsumoto
Nov 6, 2012·Acta Paediatrica·Soon M LeeChul Lee
Apr 7, 2010·Acta Paediatrica·Efraim BilavskyShai Ashkenazi
Jun 18, 2011·International Journal of Laboratory Hematology·F WeerkampUNKNOWN ADdifVIA Working Group
Apr 23, 2014·International Journal of Laboratory Hematology·D S Chabot-Richards, T I George
Apr 2, 2016·Clinica Chimica Acta; International Journal of Clinical Chemistry·Takayuki HondaMitsutoshi Sugano
Jun 20, 2006·Annals of Emergency Medicine·H Bryant NguyenUNKNOWN Emergency Department Sepsis Education Program and Strategies to Improve Survival (ED-SEPSIS) Working Group
Aug 26, 2014·Clinical Chemistry and Laboratory Medicine : CCLM·Paul Froom, Mira Barak
Jul 13, 2012·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Guohui QiaoJianzhong Wang
Dec 6, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Danthanh HoangAshraf Gad
May 6, 2015·The American Journal of Emergency Medicine·Eileen ShiEdward M Castillo
Apr 19, 2015·Critical Care : the Official Journal of the Critical Care Forum·Tracey Anne MareKenneth Alun Brown
Mar 20, 2014·Clinica Chimica Acta; International Journal of Clinical Chemistry·Kazuhiko KotaniToshiyuki Yamada
Dec 9, 2008·International Journal of Surgery·Baris D Yildiz, Osman Abbasoglu
Jul 1, 2014·Clinica Chimica Acta; International Journal of Clinical Chemistry·Jong Gyun AhnKi Hwan Kim
Feb 14, 2015·Clinics in Laboratory Medicine·Edward C C Wong
Jun 10, 2016·Journal of Perinatology : Official Journal of the California Perinatal Association·B C MacQueenH M Yaish
Oct 19, 2016·Clinical and Experimental Emergency Medicine·Joon Woo LeeYong Sung Cha
Oct 17, 2016·Rheumatology·Fabio E OspinaGabriel J Tobón
Apr 19, 2005·Expert Review of Molecular Diagnostics·Bruce H Davis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.