Clinical utility of viral quantification as a tool for disease monitoring

Expert Review of Molecular Diagnostics
M Schutten, H G M Niesters

Abstract

The possibility to detect viral DNA or RNA in a quantitative manner has already contributed significantly to the management and diagnosis of viral infections, as well as to the understanding of virus-host interactions. New developments in amplification techniques based on real-time detection, as well as automation of the whole process, will soon be introduced in a diagnostic laboratory setting, thereby enabling a rapid turnaround time to generate both quantitative and qualitative results. New guidelines for disease management, as well as extensive quality control and standardization programs must be introduced.

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Citations

Jul 24, 2002·Biochemical and Biophysical Research Communications·Ming-Liang HeHsiang-fu Kung
Feb 5, 2003·Journal of Virological Methods·Mark R SchleissDavid I Bernstein
Jan 26, 2008·Emerging Infectious Diseases·Darja DuhTatjana Avsic-Zupanc
Jul 15, 2005·Expert Review of Molecular Diagnostics·Stephen A Bustin
Jul 5, 2008·Expert Review of Molecular Diagnostics·Martin Schutten
Sep 5, 2007·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·M SchuttenH G M Niesters
Oct 19, 2004·Molecular and Cellular Probes·Xiao Mou PengGang Li
Mar 31, 2016·Future Microbiology·Gilbert GreubKatia Jaton
Dec 31, 2005·Journal of Virological Methods·Paolo PugnaleFrancesco Negro
Apr 23, 2011·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Ali KayaAbdülaziz Gültürk
Sep 21, 2005·Clinical Science·Stephen A Bustin, Reinhold Mueller

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