Clinical Utility of Weekly Laboratory Testing in the Outpatient Management of Preeclampsia and Gestational Hypertension

AJP Reports
John A MorganDavid F Lewis

Abstract

Objective  To investigate the utility of obtaining weekly laboratory testing in patients managed as an outpatient for gestational hypertension and preeclampsia without severe features. Study Design  A multisite retrospective cohort study was performed evaluating preterm women diagnosed with gestational hypertension/preeclampsia managed in an outpatient setting between gestational ages of 23 0/7 and 36 6/7 . Patients were divided into two groups: weekly laboratory evaluation (laboratories group) and a no laboratories group. The primary study outcome was composite maternal morbidity including more than one of the following: development of severe features, HELLP syndrome, eclampsia, placental abruption, maternal intensive care unit admission, or maternal death. Results  A total of 204 patients were included in this study, laboratories group ( n  = 120) and no laboratories group ( n  = 84). The laboratories group was older (28.8 vs. 26.6 years, p  = 0.02), had a higher rate of chronic hypertension (44 [36.7%] vs. 17 [20.2%], p  = 0.01), and more often experienced the primary composite outcome (53 [44.2%] vs. 24 [28.5%], p  = 0.02). No patients in our cohort were delivered for abnormal laboratory values. Conclusion  This study found...Continue Reading

Citations

Jun 5, 2020·Obstetrics and Gynecology·Christina M DuzyjChristina S Han

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