Clinical validation of a non-invasive electrodermal biofeedback device useful for reducing chronic perceived pain and systemic inflammation

Hormones : International Journal of Endocrinology and Metabolism
George Chrousos, Dario Boschiero

Abstract

This study was performed to evaluate the potential clinical usefulness of a new non-invasive electrodermal biofeedback device in reducing perceived pain levels and chronic systemic inflammation. This multicenter study was designed and coordinated by BioTekna, included 20 general practice medical centers, took place between June 2010 and January 2011, and was validated clinically at the National and Kapodistrian University of Athens, Greece. The study participants were 1015 Caucasian men (401) and women (614), while the placebo-treated controls were 950 Caucasian men (500) and women (450). Patients were aged between 30 and 86 years (average age about 50 years) and all suffered from chronic pain and other medically unexplained symptoms (MUS). The RegMatEx electrodermal biofeedback device (brand BioTekna - Biomedical Technologies, Marcon, Venice, Italy) was used to evaluate the clinical efficacy of electrodermal biofeedback in reducing the level of pain perceived by decreasing the chronic systemic inflammation of the subjects. All subjects received 6 × 30 min sessions of electrodermal or placebo biofeedback given twice a week over 3 weeks. Perceived pain was evaluated using the Numeric Rating Scale (NRS) for pain, while systemic i...Continue Reading

References

Jul 17, 1999·Immunopharmacology·C MoldT W Du Clos
Mar 31, 2000·The Clinical Journal of Pain·E K BreivikE Skovlund
Oct 3, 2000·The Clinical Journal of Pain·R J Mannion, C J Woolf
Oct 6, 2000·Anesthesiology·F M Perkins, H Kehlet
Dec 20, 2002·Nature·Kevin J Tracey
Apr 15, 2005·The New England Journal of Medicine·Steven Woloshin, Lisa M Schwartz
Jul 8, 2005·Journal of Clinical Nursing·Amelia Williamson, Barbara Hoggart
Aug 13, 2005·European Journal of Pain : EJP·Harald BreivikDerek Gallacher
Jun 3, 2009·Nature Reviews. Endocrinology·George P Chrousos
Nov 29, 2014·European Journal of Clinical Investigation·Constantine TsigosGeorge P Chrousos
Jul 20, 2016·European Journal of Clinical Investigation·Charikleia StefanakiGeorge P Chrousos
Jun 20, 2018·Scandinavian Journal of Pain·Tony O'Brien, Harald Breivik

❮ Previous
Next ❯

Citations

Aug 28, 2020·Neuropsychological Rehabilitation·Carina SanderHelmut Hildebrandt
Jan 15, 2022·Hormones : International Journal of Endocrinology and Metabolism·George P ChrousosDario Boschiero

❮ Previous
Next ❯

Software Mentioned

BioTekna
RegMatEx

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.