Clinical validity of the Mattis Dementia Rating Scale in differentiating mild cognitive impairment in Parkinson's disease and normative data

Dementia and Geriatric Cognitive Disorders
Ondrej BezdicekEvžen Růžička

Abstract

The aim of the present study was to provide normative data and determine the validity of the Czech version of the Mattis Dementia Rating Scale 2 (czDRS-2) in screening for mild cognitive impairment in Parkinson's disease (PD-MCI) based on the Movement Disorder Society (MDS) Level II criteria. For validation purposes, 41 healthy controls (HC), 46 patients with PD-NI (Parkinson's disease, no impairment) and 41 patients with PD-MCI (all groups assessed by the MDS Level II criteria for PD-MCI) were matched according to age and education. With screening and diagnostic cutoff scores determined at ≤139 points, the czDRS-2 showed a sensitivity of 78% and a specificity of 88% in the detection of PD-MCI versus HC and a sensitivity of 78% and a specificity of 76% in the detection of PD-MCI versus PD-NI. The AUC (95% confidence interval) for the czDRS-2 was 84% (75-93) and 82% (73-91), respectively. We report percentile values for 286 subjects from the Czech population stratified by education level. Our results show that the czDRS-2 is a valid instrument at Level I for screening PD-MCI and support its construct validity and diagnostic equivalence in a cross-cultural setting.

Citations

Jul 5, 2016·Neuroscience and Biobehavioral Reviews·Tetsuya AsakawaYing Xia
Mar 24, 2017·International Journal of Geriatric Psychiatry·Elina BoychevaFélix Bermejo-Pareja
Jan 18, 2017·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Jiri MichalecTim Shallice
Mar 10, 2017·The Clinical Neuropsychologist·Ondrej BezdicekEvžen Růžička
Jul 19, 2020·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Adela Fendrych MazancovaOndrej Bezdicek
Nov 24, 2017·Movement Disorders : Official Journal of the Movement Disorder Society·Matej SkorvanekUNKNOWN members of the MDS Rating Scales Review Committee
Feb 19, 2019·Movement Disorders : Official Journal of the Movement Disorder Society·Taylor R HendershottKathleen L Poston
Apr 17, 2021·Neuropsychology Review·Elizabeth R WallaceLisa M Koehl
Jul 27, 2021·Movement Disorders Clinical Practice·Marta StatuckaMelanie Cohn

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