Clinical value of abnormal findings on brain magnetic resonance imaging in patients with intravascular large B-cell lymphoma

Annals of Hematology
Yoshiaki AbeKosei Matsue

Abstract

To investigate the prevalence and clinical value of abnormal findings detected via brain magnetic resonance imaging (MRI) in patients with intravascular large B-cell lymphoma (IVLBCL), we identified 33 patients with IVLBCL pathologically diagnosed and evaluated with pretreatment brain MRI. Abnormal findings on brain MRI were categorized into four patterns: (1) hyperintense lesion in the pons on T2-weighted imaging (T2WI), (2) nonspecific white matter lesions, (3) infarct-like lesions, and (4) meningeal thickening and/or enhancement. Abnormal cerebral findings were detected in 29 patients (87.9%). Hyperintense lesion in the pons was the most common finding (n = 19 (57.6%) patients), followed by nonspecific white matter lesions (n = 14 (42.4%) patients), infarct-like lesions (n = 8 (24.2%) patients), and meningeal thickening and/or enhancement (n = 4 (12.1%) patients). Impaired consciousness was seen in most of the patients with infarct-like lesions (87.5%) but less frequently in patients with hyperintense lesion in the pons (47.4%). We reviewed brain MRI findings in 39 patients with diffuse large B cell lymphoma with central nervous system (CNS) involvement and/or high-risk extranodal lesions for CNS involvement as a control gro...Continue Reading

References

Sep 1, 1988·Radiology·G M MillerJ P Whisnant
Mar 10, 2004·Neurology·M J KupersmithH J Mitnick
Oct 6, 2004·British Journal of Haematology·Andrés J M FerreriUNKNOWN International Extranodal Lymphoma Study Group (IELSG)
May 22, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Magdalena Martusewicz-BorosRenata Langfort
Jun 20, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Maurilio PonzoniShigeo Nakamura
Dec 7, 2007·Mayo Clinic Proceedings·Noboru AsadaKosei Matsue
Mar 10, 2010·Archives of Neurology·Shigeki YamadaMasaaki Saiki
Apr 24, 2010·Cancer Science·Kazuyuki ShimadaUNKNOWN IVL Study Group in Japan
Oct 20, 2010·Annals of Hematology·Kosei MatsueMasami Takeuchi
Dec 17, 2011·AJNR. American Journal of Neuroradiology·A YamamotoS Furui
Nov 26, 2013·Brain : a Journal of Neurology·Akiko YokosekiIzumi Kawachi
Jun 6, 2015·Journal of Medical Case Reports·Eri KawataNobuhiko Uoshima

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Citations

Mar 9, 2019·Acta neurologica Belgica·Eugenia RotaNicola Morelli
Sep 21, 2021·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Andrea PorzionatoRaffaele De Caro

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