Clinical variables associated with disability in leprosy cases in northeast Brazil

Journal of Infection in Developing Countries
Victor S SantosVera Lúcia Corrêa Feitosa

Abstract

The clinical outcomes of leprosy include complications such as physical disabilities and deformities that vary according to the degree of impairment of nerve trunks. Knowledge of the factors that lead to the development of these complications is important for disability prevention programs. This study aimed to evaluate clinical factors associated with the occurrence of physical disability in leprosy cases. This was a retrospective study of 2,358 cases of leprosy in Aracaju, northeast Brazil, between 2001 and 2011. Analysis was done using the Chi-square test and logistic regression model. Significant factors associated with disability were found to be male gender, having more than two affected nerves, multibacillary leprosy classification, leprosy reaction, and lepromatous leprosy. The multivariate analysis revealed that the associated factors included having more than two affected nerves, leprosy reaction (adjusted odds ratio [aOR]: 2.02, 95% confidence interval [CI]: 1.36 to 3.01), the multibacillary form (aOR: 2.74, 95% CI: 1.84 to 4.08), and lepromatous leprosy (aOR: 4.87, 95% CI: 2.86 to 16.08). The number of affected nerves, leprosy reaction, operational classification, and clinical presentation were identified as the main...Continue Reading

Citations

May 3, 2020·International Journal of Dermatology·Caroline Baima de MeloEuzenir Nunes Sarno
Oct 14, 2017·PLoS Neglected Tropical Diseases·Edessa NegeraDiana N Lockwood
Jul 25, 2019·Revista Da Sociedade Brasileira De Medicina Tropical·Carlos Dornels Freire de SouzaVictor Santana Santos
Sep 7, 2018·Transactions of the Royal Society of Tropical Medicine and Hygiene·Joseph N ChukwuKingsley N Ukwaja

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