Clinically derived early postoperative pain trajectories differ by age, sex, and type of surgery

Pain
Patrick J TigheRoger B Fillingim

Abstract

The objective of this study was to determine the effects of age, sex, and type of surgery on postoperative pain trajectories derived in a clinical setting from pain assessments in the first 24 hours after surgery. This study is a retrospective cohort study using a large electronic medical records system to collect and analyze surgical case data. The sample population included adult patients undergoing nonambulatory nonobstetric surgery in a single institution over a 1-year period. Analyses of postoperative pain trajectories were performed using a linear mixed-effects model. Pain score observations (91,708) from 7293 patients were included in the statistical analysis. On average, the pain score decreased about 0.042 (95% confidence interval [CI]: -0.044 to -0.040) points on the numerical rating scale (NRS) per hour after surgery for the first 24 postoperative hours. The pain score reported by male patients was approximately 0.27 (95% CI: -0.380 to -0.168) NRS points lower than that reported by females. Pain scores significantly decreased over time in all age groups, with a slightly more rapid decrease for younger patients. Pain trajectories differed by anatomic location of surgery, ranging from -0.054 (95% CI: -0.062 to -0.046) ...Continue Reading

References

Mar 31, 2000·The Clinical Journal of Pain·E K BreivikE Skovlund
Jan 18, 2006·The Journal of Pain : Official Journal of the American Pain Society·Larry F ChuMartin S Angst
May 16, 2006·Lancet·Henrik KehletClifford J Woolf
Nov 22, 2007·Journal of Biomedical Informatics·Dean F SittigDavid W Bates
Apr 25, 2008·British Journal of Anaesthesia·W A Macrae
May 20, 2008·British Journal of Anaesthesia·H BreivikA Stubhaug
Jun 25, 2008·The Clinical Journal of Pain·Larry F ChuDavid Clark
Jul 19, 2008·Anesthesia and Analgesia·Robert W Hurley, Meredith C B Adams
May 5, 2009·The Journal of Pain : Official Journal of the American Pain Society·Roger B FillingimJoseph L Riley
Jul 22, 2010·The New England Journal of Medicine·David Blumenthal, Marilyn Tavenner
Sep 8, 2010·Journal of the American Medical Informatics Association : JAMIA·Jason A LymanDon E Detmer
Jan 18, 2011·The Journal of Pain : Official Journal of the American Pain Society·C Richard ChapmanDavid H Bradshaw
Sep 20, 2011·Best Practice & Research. Clinical Anaesthesiology·Julia C ColdreyPamela E Macintyre
Jan 17, 2012·The Journal of Pain : Official Journal of the American Pain Society·David RuauAtul J Butte
Jun 26, 2013·British Journal of Anaesthesia·E J Bartley, R B Fillingim
Dec 7, 2013·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Patrick James TigheRoger Fillingim
Jul 22, 2014·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Patrick J TigheRoger B Fillingim

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Citations

Aug 27, 2015·Current Opinion in Anaesthesiology·Manuel P Pereira, Esther Pogatzki-Zahn
Jul 12, 2016·Best Practice & Research. Clinical Anaesthesiology·Thomas F BendtsenJens Børglum
Jun 16, 2016·Journal of Clinical Nursing·Ann Kristin BjørnnesMarit Leegaard
Jul 28, 2016·International Journal of Nursing Studies·Alexander AvianAndrea Berghold
Oct 21, 2016·International Journal of Surgery·I SellbrantJ G Jakobsson
Feb 7, 2018·Techniques in Orthopaedics : TIO·Linda Le-WendlingPatrick Tighe
Oct 20, 2018·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Juan C MoraCameron R Smith
Aug 3, 2019·Journal of the Chinese Medical Association : JCMA·Wen-Kuei ChangKuang-Yi Chang
Dec 9, 2016·Disability and Rehabilitation·Susan M HaywardMark A Stokes
May 22, 2020·Current Anesthesiology Reports·Lisa V Doan, Jeanna Blitz
Apr 23, 2020·International Journal of Colorectal Disease·Margaretha LindbergKarl A Franklin
Sep 8, 2019·The Journal of Pain : Official Journal of the American Pain Society·Kristin L SchreiberThomas Van De Ven
Mar 19, 2021·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Emine O BaymanJennifer A Rabbitts
Jul 16, 2021·Journal of the American College of Surgeons·Hayato ShimoyamaNobutsugu Abe
Aug 20, 2021·Neurobiology of Pain·David BrennerSiobhain M O'Mahony
Sep 24, 2021·Regional Anesthesia and Pain Medicine·Edward R MarianoAsokumar Buvanendran

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