PMID: 18411132Jul 1, 1990Paper

Clinically useful calcitonin assays

Trends in Endocrinology and Metabolism : TEM
W B Carter, H Heath

Abstract

Calcitonin assays are essential tools for research into calcitonin (CT) and C-cell physiology and pathophysiology. Several existing radio immunoassays for CT, based on polyclonal antisera, are generally reliable for detection and follow-up of patients having medullary thyroid carcinoma. Occasionally, however, these assays suffer from problems of specificity and sensitivity. Two-site immunometric techniques for CT offer potential for great improvement in sensitivity, specificity, and turnaround time over those based on classical competitive-binding radioimmunoassays.

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Citations

Jan 11, 2000·Domestic Animal Endocrinology·H A HazewinkelJ A Mol
Dec 1, 1992·European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies·A ZinkF Raue

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