Clinicians' views on the feasibility of surgical randomized trials in urogynecology: results of a questionnaire survey.

Neurourology and Urodynamics
Evangelia BakaliDavid Taylor

Abstract

To survey the views of clinicians (urologists and gynecologists) about a proposed randomized surgical trial comparing two approaches for the treatment of women with urinary incontinence and vaginal prolapse. A questionnaire survey nested within a pilot randomized controlled trial of colposuspension versus anterior repair plus TVT (CARPET1) for women with incontinence and anterior vaginal prolapse. Members of the UK Continence Society, British Society of Urogynaecology, and International Continence Society were sent a single electronic mailing of semi-structured questionnaires containing closed and open questions and free text response boxes. Free text responses were analyzed using a thematic qualitative analysis. One hundred fifty-seven questionnaires were returned, from a potential total of 400 from UK and 1,700 international respondents. Fifty-eight percent thought the trial ethical, 44% desirable, and 47% feasible. Thirty-three percent would recruit to the full study, and 22% would enroll themselves or their partner. Analysis of free text responses identified three themes impacting participation: issues of patient choice and consent; clinicians' views of perceived benefit and complications of the two arms; and issues about t...Continue Reading

References

Mar 1, 1991·Journal of Medical Ethics·N JohnsonW Brazier
Jul 16, 1987·The New England Journal of Medicine·B Freedman
Dec 2, 1999·Journal of Clinical Epidemiology·S RossR Prescott
Jan 1, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·V A JenkinsM Sawtell
Dec 2, 2004·Obstetrics and Gynecology·Marie Fidela R ParaisoMatthew D Barber
Jan 8, 2005·BMJ : British Medical Journal·P J DevereauxGordon H Guyatt
Feb 1, 2006·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·J D HarrisonM J Solomon
Sep 8, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·H C KitchenerUNKNOWN COLPO Study Group
Mar 24, 2007·Diseases of the Colon and Rectum·Christopher M ByrneJames D Harrison
Jul 17, 2007·Surgery·James D HarrisonStephen Clarke
Dec 7, 2007·American Journal of Obstetrics and Gynecology·Kathryn L BurgioUNKNOWN Pelvic Floor Disorders Network
Apr 23, 2008·Archives of Surgery·James D HarrisonStephen Clarke
Apr 26, 2008·Surgery·Jane M YoungPhyllis Butow
May 16, 2008·Contemporary Clinical Trials·Isabel de SalisJenny Donovan
Jul 16, 2008·Journal of Clinical Epidemiology·Jenny L DonovanUNKNOWN ProtecT Study Group
Aug 30, 2008·BJOG : an International Journal of Obstetrics and Gynaecology·C E TurnerH Phipps
Nov 14, 2008·Journal of Health Services Research & Policy·Isabel de SalisJenny Donovan
Jan 10, 2009·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Catherine E TurnerHala Phipps
Jul 25, 2009·Clinical Trials : Journal of the Society for Clinical Trials·Linda BrubakerSharon L Tennstedt
Sep 29, 2009·Lancet·Jeffrey S BarkunJan Vandenbroucke
Sep 29, 2009·Lancet·Patrick L ErginaJan Vandenbroucke

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Citations

Jul 23, 2011·Neurourology and Urodynamics·Evangelia BakaliDouglas G Tincello
Feb 28, 2015·Journal of Minimally Invasive Gynecology·Cecile A Unger, Matthew D Barber
Aug 1, 2012·The Journal of Bone and Joint Surgery. American Volume·Vanessa A ScholtesRudolf W Poolman
Aug 2, 2017·The Cochrane Database of Systematic Reviews·Abigail A FordJoseph A Ogah

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