PMID: 29478980Feb 27, 2018Paper

Clinico-pathogenic aspects of osteodeficiency in osteoarthritis in combination with chronic pancreatitis

Wiadomości lekarskie : organ Polskiego Towarzystwa Lekarskiego
Liliy S BabinetsOksana Ya Drapak

Abstract

Introduction: Pathology of the musculoskeletal system creates a number of important and complex medical problems affecting the economic situation of society, health and quality of life of individuals and their families. One of these problems and the most common disease of the joints which is diagnosed in 20% of the population of the planet is osteoarthritis (OA). The aim: The article deals with modern views on the problem of comorbidity of osteoarthritis, chronic pancreatitis and osteodefiсiency. Dual energy X-ray densitometry data were analyzed, as well as indicators of activation of lipid peroxidation (malonic aldehyde), antioxidant protection system (superoxide dismutase and SH-group, ceruloplasmin, сatalase) and tissue destruction (oxyproline). Materials and Methods:The complex examination of 72 patients was made. Patients were divided into two groups: 30 patients with OA and 42 - with OA in combination with CP. The control group included 20 apparently healthy individuals. Evaluation of CT scan was performed using Dual Energy X-Ray Absorptiometry - DXA by Lunar corp. (Madison, WI) - Lunar DPX-A No. 2589 in the lumbar region of the vertebral column. The evaluation of the indicators was carried out in accordance with WHO reco...Continue Reading

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