PMID: 8582068Oct 1, 1995Paper

Clinico-pathological predictors of recurrence for acinic cell carcinoma

Clinical Otolaryngology and Allied Sciences
C I TimonP Gullane

Abstract

The biological behaviour of acinic cell carcinomas, even if well differentiated, is unpredictable. We studied 45 patients with acinic cell carcinoma followed-up from 10 to 379 months (5 year recurrence-free and survival rate of 69% and 81% respectively), and compared clinico-pathological parameters with outcome. The presence of a predominately solid architecture was strongly associated with a poor outcome (P < 0.01) and this was the only independent prognostic variable when log rank testing was performed. Tumour size (> 2.75 cm) was a significant predictor of recurrent deep parotid lobe involvement, the presence of cervical nodal disease and lymphocytic infiltration, although not significant, factors showed a tendency towards recurrence. For acinic cell carcinoma, the predominant solid architecture would appear to be a strong predictor of recurrence.

References

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Citations

Sep 9, 1999·Otolaryngologic Clinics of North America·D H Rice
Mar 4, 2000·International Journal of Pediatric Otorhinolaryngology·X CarratL Traissac
Jan 13, 2010·Hematology/oncology and Stem Cell Therapy·Nabil Al-ZaherBassam Sulaiman Al-Kayyali
Jan 11, 2012·Clinical and Experimental Otorhinolaryngology·Wonjae ChaKwang Hyun Kim
Feb 4, 2012·The American Journal of Surgical Pathology·Simion I ChioseaRaja R Seethala
Jul 30, 1999·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·R DoiH Ito

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