Clinicomicrobiological review of Nocardia keratitis

Cornea
M S SridharG N Rao

Abstract

To present the clinical profile, laboratory results, and outcome of treatment in 16 patients with Nocardia keratitis. A retrospective review of 16 culture-proven cases of Nocardia keratitis was done. Clinical and microbiologic data were analyzed. Nocardia constituted 1.7% of laboratory-confirmed bacterial keratitis and was seen predominantly in male subjects (13 of 16) with a mean age of 39.1 years. Although the predisposing factor was unknown in the majority, a definite history of trauma was present in four (25%) cases. Patchy stromal infiltrates were seen in 12 patients. Wreath pattern of infiltrates (six of 16) and hypopyon (nine of 16) were notable features. Nocardia was detectable in corneal scrapings of 10 patients with Gram stain and all patients with 1% acid-fast preparation (six of six). Nocardia asteroides was the causative agent in all except one (N. caviae). All isolates were sensitive to gentamicin; however, topical 30% sulfacetamide was the preferred drug for treatment. Favorable outcome (healed scar) was achieved in 11. Although Nocardia keratitis is a rare condition, a high index of clinical suspicion should be kept in agricultural workers or in patients with trauma who have patchy stromal infiltrates. Sulfonami...Continue Reading

Citations

Apr 20, 2010·Japanese Journal of Ophthalmology·Hideaki KawakamiKiyofumi Ohkusu
Jul 4, 2012·International Ophthalmology·Jeena MascarenhasNisha R Acharya
Jan 15, 2010·Journal of Ocular Biology, Diseases, and Informatics·Firoozeh RahimiReza Soltani Mogaddam
Mar 29, 2001·Survey of Ophthalmology·M S SridharG N Rao
Aug 30, 2001·Survey of Ophthalmology·A Ramsay, S Lightman
Jun 20, 2001·Cornea·M S SridharG N Rao
Apr 7, 2007·Cornea·Prajna LalithaMuthaiah Srinivasan
Nov 2, 2011·BMC Infectious Diseases·Elodie TrichetLouis Hoffart
Apr 18, 2008·Indian Journal of Ophthalmology·M SrinivasanC N Prashanth
Apr 24, 2009·Current Opinion in Ophthalmology·Prajna Lalitha
Sep 30, 2015·Cornea·Ravi PatelSeth M Pantanelli
Jul 30, 2004·Clinical & Experimental Ophthalmology·C Muniswamy KalavathyPhilip A Thomas
Jan 28, 2014·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Hideaki KawakamiHiroshige Mikamo
Dec 9, 2017·Eye & Contact Lens·Joséphine BehaegelCarina Koppen
Oct 11, 2017·Royal Society Open Science·Julieta C MartinelliMarcelo M Rivadeneira
Aug 28, 2019·Eye & Contact Lens·Aimee VernerVishal Jhanji
Feb 24, 2006·European Journal of Ophthalmology·S MatuskaR Brancato
Dec 25, 2019·Current Eye Research·Pranita SahayJeewan S Titiyal
Dec 3, 2020·Journal of Ophthalmic Inflammation and Infection·Mohammad SoleimaniAlireza Izadi
Mar 6, 2021·American Journal of Ophthalmology Case Reports·Eileen L ChangHenry D Perry
Jul 17, 1999·Journal of Clinical Microbiology·S Sharma, M S Sridhar

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Related Papers

Indian Journal of Ophthalmology
M SrinivasanC N Prashanth
International Ophthalmology
Atsushi MizotaYuzuru Mikami
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
T A SchiffJ M Brown
© 2021 Meta ULC. All rights reserved