Clinicopathologic analysis of 7 cases of oral schwannoma and review of the literature

Annals of Diagnostic Pathology
Pedro Paulo de Andrade SantosLélia Batista de Souza

Abstract

Schwannomas, also known as neurilemmomas, are uncommon neoplasms apparently derived from Schwann cells. The growth of these tumors causes displacement and compression of the nerve of origin. Schwannomas are usually solitary lesions but can be multiple when associated with neurofibromatosis. Anti-S100 protein is the most widely used antibody for the identification of this neoplasm. Surgical excision is the treatment of choice for schwannomas, with few and controversial reports of recurrence or malignant transformation. The present article reports 7 additional cases of oral schwannoma, and the literature is reviewed regarding clinicopathologic features, immunohistochemical findings, differential diagnosis, and therapeutic management of this benign neural tumor.

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Citations

Jul 3, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Alexandra R MolinaAsit R Khandwala
Feb 21, 2014·Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research·Sangeeta P WanjariSatyajitraje A Tekade
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Apr 1, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Ashish RanjanSunil More

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