Clinicopathologic analysis of surgically proven intraductal papillary mucinous neoplasms of the pancreas in SNUH: a 15-year experience at a single academic institution.

Langenbeck's Archives of Surgery
Dae Wook HwangSun-Whe Kim

Abstract

The clinical importance of intraductal papillary mucinous neoplasm of the pancreas (IPMN) has been increasing with a large number of newly diagnosed IPMN. This study was designed to explore the characteristics of resected IPMN and to determine the predictive factors for malignant and invasive IPMN. Retrospective review of a prospectively collected database was performed on 187 consecutive patients following IPMN surgery between 1994 and 2008 at a tertiary institute. The main duct type IPMN was radiologically defined as main pancreatic duct dilation >5 mm rather than previously defined ≥10 mm. The morphologic types of IPMN included 28 main duct (IPMN-M, 15.0%), 118 branch duct (IPMN-Br, 63.1%), and 41 mixed (IPMN-Mixed, 21.9%) IPMNs. There were 23 patients with adenoma, 106 borderline atypia, 15 carcinoma in situ, and 43 invasive carcinoma. Sixty-nine extrapancreatic malignancies were diagnosed in 61 (32.6%) patients. Based on multivariate analysis, IPMN-M was statistically significant predictor of malignancy/invasiveness (p = 0.013/p = 0.028). In patients with IPMN-Br, the presence of mural nodule was a predictive factor for malignancy/invasiveness (p = 0.005/p = 0.002). In patients with IPMN-Mixed, mural nodule (p = 0.038/p = ...Continue Reading

References

Oct 21, 2005·World Journal of Gastroenterology : WJG·Terumi KamisawaAtsutake Okamoto
Dec 6, 2005·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Masao TanakaUNKNOWN International Association of Pancreatology
Apr 18, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Philippe LévyPhilippe Ruszniewski
Apr 28, 2007·World Journal of Gastroenterology : WJG·Seung Eun LeeSun-Whe Kim
Jul 17, 2007·Gastroenterology·J Ruben RodriguezCarlos Fernández-Del Castillo
Sep 26, 2007·Annals of Surgery·C Max SchmidtKeith D Lillemoe
Oct 6, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Joshua A WatersKeith D Lillemoe

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Citations

Mar 30, 2013·World Journal of Gastroenterology : WJG·Bin XuWen-Hui Lou
Nov 22, 2012·Gut and Liver·Dong-Won AhnYong Bum Yoon
Jan 23, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·John B AmmoriPeter J Allen
Apr 20, 2014·International Journal of Surgery·H G BegerC Vasilescu
Jul 6, 2014·Virchows Archiv : an International Journal of Pathology·Koji ShindoYoshinao Oda
Nov 15, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Temel TirkesFatih Akisik
Jan 25, 2012·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·S FritzJ Werner
Jan 28, 2014·Hepatobiliary & Pancreatic Diseases International : HBPD INT·Adriana Handra-Luca
Oct 8, 2013·Gastrointestinal Endoscopy·Khaled AbdeljawadMohammad Al-Haddad
Aug 28, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Rupjyoti Talukdar, D Nageshwar Reddy
Jun 13, 2012·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Masao TanakaUNKNOWN International Association of Pancreatology
Nov 6, 2015·ACS Applied Materials & Interfaces·Andrey C SoaresOsvaldo N Oliveira
Oct 3, 2014·Gastroenterology Research and Practice·Marina PainiMassimo Falconi
Jun 26, 2015·North American Journal of Medical Sciences·Norman Oneil MachadoKhalifa Al Wahibi
Feb 19, 2015·World Journal of Surgery·H G BegerM H Schoenberg
Mar 4, 2015·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Hans G BegerBertram Poch
Aug 16, 2016·Advances in Surgery·Alexandra M Roch, Christian Max Schmidt
Aug 28, 2016·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Teppei YoshiokaTetsuo Takehara
May 19, 2017·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Linda M PakPeter J Allen
Feb 3, 2018·Annals of Surgical Oncology·Pauline DuconseilOlivier Turrini
Jul 14, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Hans G BegerBertram Poch
Nov 13, 2019·Khirurgiia·V I PanteleevA G Kriger
Dec 7, 2019·Surgery Today·Seiko Hirono, Hiroki Yamaue
Sep 19, 2019·Nature Reviews. Gastroenterology & Hepatology·Nadine C M van HuijgevoortMarc G Besselink
Aug 8, 2019·Annals of Surgical Treatment and Research·Jae Seung KangJin-Young Jang
Apr 20, 2017·Digestive Diseases and Sciences·Jon M Gerry, George A Poultsides
Mar 12, 2015·World Journal of Gastroenterology : WJG·Mathieu DaudéBarbara Bournet
Sep 10, 2018·Current Treatment Options in Gastroenterology·Ijm LevinkD L Cahen

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