PMID: 8943185Jan 1, 1997Paper

Clinicopathologic differences between long-term and short-term postoperative survivors with advanced gallbladder carcinoma

World Journal of Surgery
Kazuo ChijiiwaM Tanaka

Abstract

The objective of this study was to determine histopathologic factors that influence the failure or success of extended cholecystectomy and more aggressive surgery to attain long-term survival in patients with advanced carcinoma of the gallbladder. Of 46 patients with carcinoma of the gallbladder who had undergone surgical resection, 36 had advanced carcinoma invading to or beyond the subserosal layer. Among these 36 patients were 10 long-term survivors (> 5 years) and 11 short-term survivors who died of recurrence (< 37 months) after extended cholecystectomy or more extensive surgery. Factors were compared between the two groups. Significant factors observed in the long-term survivors were the depth of invasion limited to the subserosal layer (p < 0.05), hepatic infiltration < 5 mm (p < 0.01), histologic grade of papillary or well differentiated adenocarcinoma (p < 0.01), absent or minimal venous, lymphatic, and perineural invasion (p < 0.01), and lymph node metastasis limited to the hepatoduodenal ligament (p < 0.05). It was concluded that the patients with subserosal invasion have a hope for long-term survival by extended cholecystectomy or more aggressive surgery when hepatic infiltration and venous, lymphatic, and perineura...Continue Reading

Citations

Dec 20, 2008·Journal of Hepato-biliary-pancreatic Surgery·Takenari NakataShinichi Miyagawa
May 18, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Masahiro KaiKazuhiro Kondo
Dec 25, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Sae Byeol ChoiSang Yong Choi
Jan 5, 2002·International Journal of Radiation Oncology, Biology, Physics·John J KreslDavid Nagorney
Mar 26, 1998·Baillière's Clinical Gastroenterology·V K Kapoor, I S Benjamin
May 3, 2001·Journal of the American College of Surgeons·K ChijiiwaM Tanaka
Mar 21, 1998·The British Journal of Surgery·V K Kapoor, I S Benjamin
Feb 25, 2006·AJR. American Journal of Roentgenology·Naveen KalraKusum Joshi
Dec 21, 2006·World Journal of Surgery·Takenari NakataShinichi Miyagawa
Jul 23, 2013·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Anil K AgarwalPuja Sakhuja
Oct 19, 2005·Journal of Surgical Oncology·Ryoko SasakiKazuyoshi Saito
Dec 1, 2007·Journal of Surgical Oncology·Siu Yin ChanSheung Tat Fan
May 26, 2006·Journal of Surgical Oncology·Sadiq S Sikora, Rajneesh K Singh
Aug 19, 2006·Journal of Surgical Oncology·Yoshihiro SakamotoMasatoshi Makuuchi
Dec 8, 2010·The British Journal of Surgery·H-S HanH Kim
Jul 15, 2015·Korean Journal of Hepato-biliary-pancreatic Surgery·Kyoung-Yeon HwangSung-Gyu Lee
Aug 23, 2002·The British Journal of Surgery·R YamaguchiY Nimura
Oct 30, 2009·American Journal of Clinical Pathology·Takeaki IkedaSeiyo Ikeda
Jun 17, 2016·The American Surgeon·Mohd Raashid SheikhDhiresh Rohan Jeyarajah

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.