Clinicopathologic Features and Clinical Outcomes of Esophageal Gastrointestinal Stromal Tumor: Evaluation of a Pooled Case Series

Medicine
Fan FengHongwei Zhang

Abstract

Clinicopathologic features and clinical outcomes of gastrointestinal stromal tumors (GISTs) in esophagus are limited, because of the relatively rare incidence of esophageal GISTs. Therefore, the aim of the current study was to investigate the clinicopathologic features and clinical outcomes of esophageal GISTs, and to investigate the potential factors that may predict prognosis.Esophageal GIST cases were obtained from our center and from case reports and clinical studies extracted from MEDLINE. Clinicopathologic features and survivals were analyzed and compared with gastric GISTs from our center.The most common location was lower esophagus (86.84%), followed by middle and upper esophagus (11.40% and 1.76%). The majority of esophageal GISTs were classified as high-risk category (70.83%). Mitotic index was correlated with histologic type, mutational status, and tumor size. The 5-year disease-free survival and disease-specific survival were 65.1% and 65.9%, respectively. Tumor size, mitotic index, and National Institutes of Health risk classification were associated with prognosis of esophageal GISTs. Only tumor size, however, was the independent risk factor for the prognosis of esophageal GISTs. In comparison to gastric GISTs, th...Continue Reading

References

Feb 19, 1999·AORN Journal·M Gavaghan
Apr 11, 2002·European Journal of Gastroenterology & Hepatology·Shin IijimaTomoyuki Masuda
Feb 5, 2005·Annals of Diagnostic Pathology·Anthony PadulaMarkku Miettinen
Mar 19, 2005·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·A M GouveiaM C Oliveira
Sep 1, 2005·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·N ManuS Howard
Mar 3, 2006·Journal of Gastroenterology and Hepatology·Chien-Sheng HuangMin-Hsiung Huang
May 9, 2006·The Journal of Thoracic and Cardiovascular Surgery·Ahmet BasogluLevent Yildiz
Nov 9, 2006·Archives of Pathology & Laboratory Medicine·Markku Miettinen, Jerzy Lasota
Aug 29, 2007·The Journal of Thoracic and Cardiovascular Surgery·Takaaki MasudaTakeshi Okamura
Oct 5, 2007·International Journal of Surgical Pathology·Giuseppe PortaleErmanno Ancona
Oct 24, 2007·The Annals of Thoracic Surgery·Matthew G BlumBrian Adley
Dec 15, 2007·Zeitschrift für Gastroenterologie·F-C FangS-C Lee
Nov 7, 2008·World Journal of Surgical Oncology·Gian Paolo SpinelliSilverio Tomao
Apr 22, 2009·The Annals of Thoracic Surgery·Hyun Joo LeeYong Hee Kim
Apr 22, 2009·The Annals of Thoracic Surgery·Steven MilmanMichael J Liptay
May 30, 2009·Journal of the National Medical Association·Dilip DanRajendra Persad
Oct 3, 2009·Japanese Journal of Clinical Oncology·Kazushi Miyata, Hiroyasu Igaki
Dec 22, 2009·American Journal of Clinical Pathology·Isabelle HosteinJean-Michel Coindre
Mar 9, 2010·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Peng JiangBingren Gao
Apr 29, 2010·Internal Medicine·Satoshi HamadaYoshiharu Sakai
May 1, 2010·Cell and Tissue Research·Goran RadenkovicOlivera Mitrovic
Jun 16, 2010·General Thoracic and Cardiovascular Surgery·Kazuhiro ImaiJun-ichi Ogawa
Jun 26, 2010·ANZ Journal of Surgery·Rasih YilmazGokhan Icoz
Apr 12, 2011·The Thoracic and Cardiovascular Surgeon·B-Y WangC-S Shih
Jul 1, 2011·Journal of Gastrointestinal Cancer·Elsa IannicelliVincenzo David
Jul 22, 2011·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Hiroyuki YamadaKiyohumi Yamagishi
Sep 6, 2011·The Surgical Clinics of North America·Valerie P Grignol, Paula M Termuhlen
Sep 29, 2011·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·T FardounB Meunier
Nov 10, 2011·Journal of Surgical Oncology·Markku Miettinen, Jerzy Lasota
Nov 18, 2011·Nature Reviews. Cancer·Christopher L CorlessMichael C Heinrich
May 1, 2012·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·A B ShinagareN H Ramaiya
Dec 15, 2012·World Journal of Gastroenterology : WJG·Kevin K Roggin, Mitchell C Posner
Apr 30, 2013·Lancet·Heikki JoensuuChristopher L Corless
May 25, 2013·International Journal of Surgery Case Reports·Phayvanh P SjogrenDaniel H Dunn
Oct 24, 2013·Zentralblatt für Chirurgie·C NawaraF Primavesi

❮ Previous
Next ❯

Citations

Jun 25, 2018·Esophagus : Official Journal of the Japan Esophageal Society·Tomoaki AokiYoshihiro Kakeji
Mar 26, 2020·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Yangyang ZhouQing Li
Apr 3, 2021·World Journal of Gastrointestinal Surgery·Michel Ribeiro FernandesCléber Rosito Pinto Kruel
May 1, 2021·Esophagus : Official Journal of the Japan Esophageal Society·Tomio AraiYuichiro Doki

❮ Previous
Next ❯

Methods Mentioned

BETA
surgical resection

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved