Clinicopathologic findings in a patient with serpiginous choroiditis and treated choroidal neovascularization.

Retina
J S WuW R Green

Abstract

We present the ocular clinicopathologic features of the left eye of a patient who, during a 29-year period, developed the characteristic features of progressive serpiginous choroiditis. Two areas of choroidal neovascularization were successfully treated by laser photocoagulation. The larger area of neovascularization, located in and inferior to the maculopapillary bundle area and treated with argon laser, resulted in a scar composed of hyperplastic retinal pigment with persistence of neovascularization and full-thickness destruction of the retina. A smaller area of neovascularization, located temporal to the fovea and treated by krypton laser, resulted in a fibrous scar with obliteration of the new vessels and preservation of the inner retinal layers. A diffuse and focal infiltrate of lymphocytes was present in the choroid. Often, larger aggregates of lymphocytes were present at the margin of the serpiginous lesions. The serpiginous lesions were characterized by loss of retinal pigment epithelium and the photoreceptor cell layer. The margins of most lesions had variable degrees of hyperplastic retinal pigment epithelium and some had defects in Bruch's membrane, through which fibroglial scar tissue extended into the choroid.

Citations

Aug 3, 2002·Ophthalmology·Esen Karamursel AkpekC Stephen Foster
Nov 13, 2002·Clinical & Experimental Ophthalmology·Marta Ugarte, I Michael J Wearne
Nov 21, 2002·Retina·Nancy J ChristmasJames C Folk
Jan 19, 2005·Retina·Douglas A Jabs, Esen Karamursel Akpek
Nov 15, 2011·Retina·Amod GuptaAman Sharma
Mar 23, 2011·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Julie Rodman, Joseph Pizzimenti
Feb 22, 2005·The British Journal of Ophthalmology·E BaglivoN Rao
Jun 27, 2007·The British Journal of Ophthalmology·M J GallagherC S Foster
Jun 1, 1996·The British Journal of Ophthalmology·A GiovanniniB Scassellati-Sforzolini
Sep 1, 2000·The British Journal of Ophthalmology·A A AraujoJ V Forrester
May 7, 2014·Journal of Ophthalmology·Ahmed SamyOren Tomkins-Netzer
Oct 25, 2014·Ocular Immunology and Inflammation·Lana M RifkinDebra A Goldstein
Sep 1, 2007·Ocular Immunology and Inflammation·H AbrezS Sudharshan
Jun 13, 2006·Ocular Immunology and Inflammation·Rana Altan-YayciogluGursel Yilmaz
Apr 15, 2014·Ocular Immunology and Inflammation·Ai TakahashiSusumu Ishida
Apr 2, 2013·Survey of Ophthalmology·Hossein Nazari Khanamiri, Narsing A Rao
Nov 9, 2010·Survey of Ophthalmology·Radgonde Amer, Noemi Lois
Jun 13, 2006·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Raul N G ViannaMiguel N Burnier
Apr 27, 2005·Survey of Ophthalmology·Wee-Kiak LimRobert B Nussenblatt
Jun 6, 2015·Indian Journal of Ophthalmology·Pradeep VenkateshRandeep Guleria
Apr 16, 2015·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Elizabeth WongMichael Kalloniatis
Mar 3, 2015·International Ophthalmology Clinics·Julia F Malalis, Debra A Goldstein
Oct 19, 2016·Ocular Immunology and Inflammation·Nazanin EbrahimiadibC Stephen Foster
Oct 7, 2017·The British Journal of Ophthalmology·Daniela MontorioFrancesco Bandello
Jul 1, 2009·Retinal Cases & Brief Reports·Athanasios I KotsolisLawrence A Yannuzzi
Oct 26, 2016·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Hashim Ali Khan, Muhammad Aamir Shahzad
Dec 9, 2016·Retina·Spoorti Krishna Reddy MandadiUNKNOWN for OCTA Study Group
Jun 5, 2003·Current Opinion in Ophthalmology·Esen Karamursel Akpek, Ozge Ilhan-Sarac
Jan 30, 2002·Ocular Immunology and Inflammation·E K AkpekC S Foster
Jul 19, 2019·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Angeliki Arvanitogiannis
Feb 23, 2021·American Journal of Ophthalmology Case Reports·Arash MalekiC Stephen Foster
Apr 13, 2021·American Journal of Ophthalmology·UNKNOWN Standardization of Uveitis Nomenclature (SUN) Working Group
Sep 10, 2008·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Omar S PunjabiCarmen A Puliafito
Oct 5, 2006·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Sung-Pyo ParkHyeong Gon Yu
Jun 29, 2021·European Journal of Ophthalmology·Manpreet BrarMangat Ram Dogra
Jul 23, 2021·Progress in Retinal and Eye Research·Raphael LejoyeuxJay Chhablani

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye
Omar S PunjabiCarmen A Puliafito
Seminars in Ophthalmology
Khayyam Durrani, C Stephen Foster
Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye
Steven YehR B Nussenblatt
© 2022 Meta ULC. All rights reserved