Clinicopathological analysis of oral squamous cell carcinoma among the younger age group in coastal Karnataka, India: A retrospective study

Journal of Oral and Maxillofacial Pathology : JOMFP
Riaz AbdullaYashwanth Subbannayya

Abstract

Oral squamous cell carcinoma (OSCC) primarily occurs in older age group. However, in the recent years, incidence of oral cancer in young people has been on rise worldwide. Towards this end, we sought to analyze the clinical and histopathological characteristics of OSCC in patients less than 45 years of age. The clinical and histological features of patients diagnosed with squamous cell carcinoma of the oral cavity at two hospitals in the coastal Karnataka region of South India between 1996-2012 were reviewed. The tabulation and descriptive statistics of the study were carried out. A total of 420 patients were treated for OSCC in the 17-year period (1996-2012), of which 86 (20.5 %) patients were under 45 years of age. The most common site of involvement among the young was tongue (29.07%) and buccal mucosa (27.9%) respectively. A total of 47 (54.65%) patients were either habitual chewers, smokers, or alcoholics. Pathological grading of cases classified tumors into well differentiated (34.88%), moderately differentiated (46.51%) and poorly differentiated (4.65%). The data from this study reveals that a significant proportion of the OSCC cases are observed in patients of 45 years or younger. Additionally, our study also indicated ...Continue Reading

Citations

Apr 7, 2020·Clinical and Experimental Dental Research·Kiichi HatanoTamotsu Takeuchi
Apr 28, 2020·Laryngoscope Investigative Otolaryngology·Hassan Nasser, Maie A St John
May 25, 2021·Cancer Biomarkers : Section a of Disease Markers·Varshasnata MohantyAditi Chatterjee

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BETA
biopsy

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Carcinoma, Squamous Cell

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