Clinicopathological and virological characteristics of superficially invasive squamous-cell carcinoma of the anus

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
R AranaI Etienney

Abstract

The clinicopathological and virological characteristics of anal superficially invasive squamous-cell carcinoma (SISCCA) were determined. Seventeen patients with a completely excised stage T1N0M0 anal squamous-cell carcinoma (SCC) were included in the study. The tumours were divided into superficially invasive and invasive. Patients with anal high-grade squamous intraepithelial dysplasia, which corresponded to anal intraepithelial neoplasia (AIN) Grades 2 or 3, were used as a control group. Clinicopathological and virological characteristics were investigated. Overall survival and cancer recurrence-free survival were also assessed. Of the 17 patients, 12 (70.5%) were men. Ten (58.8%) were human immunodeficiency virus positive. Seven (41%) patients met the same diagnostic criteria as those recently proposed for anal SISCCA. According to the results obtained using the polymerase chain reaction, human papillomavirus (HPV) 16 was the most commonly detected (94%) type of HPV. Twelve (70.6%) patients with an inadequate surgical margin around the tumour received adjuvant radiotherapy, including the two (11.7%) tumours that locally recurred, one of which was an anal SISCCA. Superficially invasive anal cancers differed from the other T1N...Continue Reading

References

Oct 1, 1976·Annals of Surgery·O H Beahrs, S M Wilson
May 14, 2005·International Journal of Radiation Oncology, Biology, Physics·Cécile OrtholanJean Pierre Gerard
Jul 27, 2005·The British Journal of Surgery·J H ScholefieldN F S Watson
Aug 19, 2006·ANZ Journal of Surgery·Angus J M WatsonFrank A Frizelle
Jan 27, 2009·Journal of Surgical Oncology·Frederick L Greene, Leslie H Sobin
Feb 2, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J H ScholefieldA Radcliffe
Feb 15, 2011·Cancer Cytopathology·Teresa M Darragh, Barbara Winkler
Mar 3, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Alexandra de PokomandyFrançois Coutlée
Oct 14, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Thomas ZilliAbdelkarim S Allal
Mar 20, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Rebecca A NelsonLily L Lai
Aug 13, 2013·International Journal of Cancer. Journal International Du Cancer·J Michael BerryJoel M Palefsky
Jun 21, 2014·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Robert Glynne-JonesDirk Arnold
Jul 9, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·R Glynne-JonesD Arnold
Sep 23, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·R Glynne-JonesD Arnold

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Citations

Mar 26, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M Alfa-WaliM Bower
Jan 19, 2017·The American Journal of Surgical Pathology·Yiang HuiLi Juan Wang
Dec 8, 2017·European Journal of Epidemiology·Kevin David ShieldIsabelle Soerjomataram
Sep 25, 2020·Diseases of the Colon and Rectum·J Michael Berry-Lawhorn
Jun 21, 2017·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Ian GehRichard Adams
Jul 17, 2020·International Journal of Colorectal Disease·T B PedersenM F Klein
Nov 4, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Tom A MaccabeDavid E Messenger
Apr 9, 2021·American Society of Clinical Oncology Educational Book·Rahel GhebreGypsyamber D'Souza
Aug 31, 2021·Seminars in Radiation Oncology·William Tyler Turchan, Stanley L Liauw

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