Clinicopathological characteristics and outcome of adult patients with hematuria and/or proteinuria found during routine examination

Nephron. Clinical Practice
Peicheng ShenYi Fang

Abstract

Patients with hematuria and/or proteinuria found during routine examination are commonly encountered. To define the clinicopathological characteristics and outcome of these patients, 142 patients with definite pathological diagnosis were studied retrospectively. All the 142 patients were divided into three groups: pure hematuria (HU, n = 13), concomitant hematuria and proteinuria (HUPU, n = 79), and proteinuria alone (PU, n = 50). At the time of renal biopsy, 26% of the patients had renal insufficiency and 48% of the patients had hypertension. Pathologically, IgA nephropathy (n = 67) was the most common. A total of 51 patients were enrolled into the follow-up group. Finally, urinary abnormalities disappeared in 18% of the patients, 22% of HU developed proteinuria, 21% of HUPU and 23% of PU appeared to have a distinct increase of proteinuria, and 15% of PU developed hematuria. Seven patients with normal blood pressure before became hypertensive and 6% of the patients with normal renal function initially developed renal insufficiency. The renal outcome was associated with proteinuria and tubulointerstitial lesions. Because renal pathologic change does not always coincide with clinical manifestations, patients with hematuria and/o...Continue Reading

References

Jan 1, 1976·Nephron·D W Cockcroft, M H Gault
Feb 1, 1994·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·R J HoggD A Savino
Jan 1, 1996·Kidney International·C NieuwhofP J van Breda Vriesman
Apr 1, 1997·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A KoyamaM Kobayashi
Jun 1, 1997·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M Haas
Nov 13, 1998·The New England Journal of Medicine·G Remuzzi, T Bertani
Jan 6, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·L DanielY Berland
Jan 6, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·P MaisonneuveP Boyle
Jun 10, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·P RuggenentiG Remuzzi
Aug 3, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·G D'Amico
Jun 28, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·E M BrigantiR C Atkins
Sep 22, 2001·The New England Journal of Medicine·B M BrennerUNKNOWN RENAAL Study Investigators
Oct 5, 2001·Skin Pharmacology and Applied Skin Physiology·C Garbe, A Blum
Jul 2, 2002·International Urology and Nephrology·Ozlem HarmankayaIşin Kiliçarslan
Jan 29, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Juhani MyllymäkiAmos Pasternack
Oct 22, 2004·QJM : Monthly Journal of the Association of Physicians·K M ChowC C Szeto

❮ Previous
Next ❯

Citations

Mar 17, 2007·International Journal of Clinical Practice·P ShenM Chen
May 18, 2016·Nature Reviews. Disease Primers·Kar Neng LaiRichard J Glassock
Jan 2, 2009·Pathology, Research and Practice·Jovan DimitrijevićLjubica Djukanović
Apr 13, 2019·Nephrology·See Cheng YeoJonathan Barratt
Dec 15, 2020·The American Journal of the Medical Sciences·Arun RajasekaranDana V Rizk

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

QJM : Monthly Journal of the Association of Physicians
K M ChowC C Szeto
Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
B S ChoH H Kang
© 2022 Meta ULC. All rights reserved