PMID: 8682475Jan 1, 1996Paper

Clinicopathological characteristics and surgical procedures for carcinoma of the papilla of Vater

Hepato-gastroenterology
N FutakawaT Muto

Abstract

In the present study, clinicopathological characteristics of carcinoma of the papilla of Vater and suitable operative procedures for treatment were investigated. Sixty cases (40 male and 20 female) of resected carcinoma of the papilla of Vater were studied clinicopathologically. Among the patients, a polypoid type without ulceration and an ulcer-formation type, with regard to the gross appearance, were found in 37 cases and 23 cases, respectively. Submucosal invasion, invasion to the sphincter Oddi, pancreatic parenchymal invasion and lymph node involvement were found more frequently in the ulcer-formation type than in the polypoid type without ulceration. Postoperative survival curves revealed that the prognosis was poor when either lymph node involvement, invasion to pancreatic parenchyma or ulcer formation was found. Local resection was performed in seven cases, in all of whom carcinoma was found histologically in the cut surface of the tumor. This is easily explained by the fact that mucosal spread or interstitial infiltration was frequently found even in cases with carcinoma at a relatively early stage. Local resection for carcinoma of the papilla of Vater is inadequate as a curative resection, and pylorus-preserving pancr...Continue Reading

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