Clinicopathological correlation of choroidal melanoma in Indian population: A study of 113 cases.

Oman Journal of Ophthalmology
Maneesh DhupperVikas Khetan

Abstract

To correlate the clinical presentation, tumor characteristics, and histopathological findings of choroidal melanoma in the Indian population A retrospective analysis of 113 patients of choroidal melanoma over a period of 10 years was done. Patient demography, clinical presentation, tumor characteristics, and histopathological findings were correlated. Among 113 patients histopathologically diagnosed with choroidal melanoma over 10 years, most were males. The mean age was 45.9 ± 14.84 years among which 6 (5.3%) patients were less than 20 years. Thirty-six (31.8%) patients were misdiagnosed. The mean basal diameter was 12.41 ± 1.4 mm. Mixed cell type was seen in 71 (63%) patients, while 28 (25%) patients had spindle cell type. Epithelioid cell type was present in 11 (10%) patients and necrotic cell type was seen in 3 (2%) patients. Enucleation was the primary treatment modality in 107 (94.6%) patients, while exenteration was done in 6 (5.3%) patients. Three patients with epithelioid cell type with orbital extension underwent exenteration. The mean follow-up period was 14 months. No mortality was reported at the end of 5 years in patients with longer follow-up. Malignant melanoma of the choroid is a rare occurrence. They can occur...Continue Reading

References

Nov 1, 1991·Ophthalmology·C L ShieldsH Menduke
Jan 1, 1988·Survey of Ophthalmology·K M EganD M Albert
Jan 1, 1984·Archives of Ophthalmology·C E Margo, I W McLean
Jan 1, 1982·International Ophthalmology Clinics·P K KuoB F Wu
Jul 2, 2003·American Journal of Ophthalmology·Dennis M Robertson
Jan 17, 2007·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Jens LindegaardSteffen Heegaard

❮ Previous
Next ❯

Citations

Jun 15, 2019·Singapore Medical Journal·Wendy WongLingam Gopal
Oct 5, 2017·South Asian Journal of Cancer·Prajna MeeralakshmiVenkatapathy Narendran
Feb 1, 2020·Ocular Oncology and Pathology·Pukhraj RishiKummamuri Sreelakshmi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Australian Veterinary Journal
D G Lampard, D L Morgan
Australian Journal of Ophthalmology
R L Smith, P N Henderson
Australian Journal of Ophthalmology
F P English, W B Nutting
Nihon ganka kiyo
K KojimaW Ueda
© 2021 Meta ULC. All rights reserved