Clinicopathological features of chronic inflammatory demyelinating polyradiculoneuropathy in childhood

Journal of the Neurological Sciences
N HattoriG Sobue

Abstract

The clinical, electrophysiological, and pathological findings, and the therapeutic characteristics in ten children with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), whose onset age was less than 16 years, were evaluated. The clinical progression pattern of the initial phase divided the patients into two groups. One group (six patients) showed a subacute progression for up to 2 months after onset and a subsided progression over 3 months. Three patients in this group had a preceding febrile episode. The other group (four patients) showed a chronic insidious progression for more than 3 months. The former group of patients revealed a favourable response to corticosteroid therapy as compared with the latter group. However, other clinical and laboratory features at the peak impairment were not distinguishable between these two groups. Motor dominant neuropathy was common to all patients, and only three cases showed sensory disturbance on the distal limbs. No cases revealed cranial nerve involvement. Motor and sensory nerve conduction and sural nerve biopsy studies revealed the demyelinating nature of the neuropathy. These clinicopathological features suggest that the subacute progression form frequently associate...Continue Reading

References

Jun 1, 1992·Archives of Neurology·R HughesP Payan
Feb 1, 1989·Brain : a Journal of Neurology·G SobueA Takahashi
Nov 1, 1988·Stroke; a Journal of Cerebral Circulation·R F Bloch
Feb 20, 1986·The New England Journal of Medicine·P J DyckC Swanson
Oct 1, 1985·Muscle & Nerve·G FerriereF Guzzetta
Dec 1, 1985·Brain : a Journal of Neurology·J M Jacobs, S Love
Sep 1, 1980·The Journal of Pediatrics·R V ColanJ W Benton
Oct 1, 1996·Brain : a Journal of Neurology·C O HanemannG Stoll
Jul 13, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·J L Fernández-TorreJ Berciano
Sep 18, 2001·Annals of Neurology·R A Hughes

❮ Previous
Next ❯

Citations

Sep 26, 2006·Journal of Neurology·Juan J Archelos, Franz Fazekas
Jan 19, 2011·Current Treatment Options in Neurology·Glenn Lopate, Alan Pestronk
Sep 14, 2011·Current Treatment Options in Neurology·Hugh J McMillanPeter B Kang
Mar 7, 2001·Journal of the Neurological Sciences·N HattoriG Sobue
Apr 13, 2001·Pediatric Neurology·A M Connolly
Feb 11, 2015·Journal of Clinical Apheresis·Marta LucchettaChiara Briani
Jan 10, 2012·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Antoinetta G M RiekhoffBerten P G M Ceulemans
Jul 1, 2008·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Malcolm Rabie, Yoram Nevo
Feb 6, 2007·Pediatric Neurology·Elsa RossignolMichel Vanasse
Jul 1, 2010·Muscle & Nerve·Ahmad R MohamedMonique M Ryan
Apr 18, 2006·Neuromuscular Disorders : NMD·E KararizouD Vassilopoulos
Apr 25, 2006·Neuromuscular Disorders : NMD·Gérard Said
Apr 30, 2015·Brain & Development·Sébastien CabassonJean-Michel Pedespan
Aug 19, 2007·European Journal of Internal Medicine·Arsenio PompeoNicola Genovesi
Dec 1, 2017·Journal of Clinical Neuromuscular Disease·Yohei HaradaEric L Logigian
Dec 11, 1999·Current Opinion in Neurology·R D Hadden, R A Hughes
Dec 3, 2016·Developmental Medicine and Child Neurology·Jonathan GadianMichael Absoud
Jan 7, 2015·The Cochrane Database of Systematic Reviews·Richard A C Hughes, Man Mohan Mehndiratta
Dec 1, 2017·The Cochrane Database of Systematic Reviews·Richard Ac HughesYusuf A Rajabally
Mar 1, 2002·Muscle & Nerve·Ingemar S J MerkiesPieter A Van Doorn

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.