Clinicopathological features of isolated pulmonary cryptococcosis in HIV-negative patients.

The Journal of International Medical Research
Huan-Huan WuShuang-Yan Fang

Abstract

To analyse the clinicopathological features of isolated pulmonary cryptococcosis in human immunodeficiency virus (HIV)-negative patients. This retrospective study analysed the following data from HIV-negative patients diagnosed with pulmonary cryptococcosis: demographics, underlying diseases, clinical manifestations on admission, laboratory tests, imaging data, results of histopathology, treatment options and outcomes. Sputum samples from all patients were collected and assessed for the presence of yeast or fungi. Cryptococcal antigen testing was performed for some patients. Histopathological analysis was also undertaken for some samples of lung tissue. The study analysed 37 patients (22 males). Thirteen (35.14%) patients were asymptomatic, 24 (64.86%) were symptomatic and 17 (45.95%) patients had no underlying disease. Out of 25 tested patients, 23 (92.00%) tested positive on the serum cryptococcal capsular polysaccharide antigen test. During 6 to 24 months of follow-up, all 37 patients that were either treated with or without antifungal therapy alone or combined with surgical resection showed complete recovery. One patient made a full recovery without any treatment. Early identification of pulmonary cryptococcosis in HIV-nega...Continue Reading

References

Oct 1, 1995·Clinical Microbiology Reviews·T G Mitchell, J R Perfect
Mar 20, 1999·Chest·J A AbergW G Powderly
Jul 30, 2002·QJM : Monthly Journal of the Association of Physicians·S-S JeanK-T Luh
Dec 11, 2003·Chest·Hassan F NadrousJay H Ryu
Oct 22, 2005·Respiratory Medicine·Kazuma KishiKunihiko Yoshimura
May 2, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J W BaddleyP G Pappas
Apr 9, 2009·Current Opinion in Pulmonary Medicine·Rhett M Shirley, John W Baddley
Jan 6, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·John R PerfectTania C Sorrell
Feb 2, 2010·Emerging Infectious Diseases·Eleni GalanisUNKNOWN British Columbia Cryptococcus gattii Working Group
Jan 29, 2011·Scandinavian Journal of Infectious Diseases·Kyoung Hwa ChoiYong Chul Lee
Dec 3, 2011·Critical Reviews in Microbiology·Anuradha ChowdharyJacques F Meis
Mar 13, 2012·The European Respiratory Journal·Yuan ZhangRex C Yung
Nov 17, 2012·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Jin-Quan YuRichard W Light
Dec 21, 2012·Science Translational Medicine·Gordon D BrownTheodore C White
Jan 30, 2014·Revista Da Sociedade Brasileira De Medicina Tropical·Valter Luis Iost TeodoroMaria José Soares Mendes-Giannini
Aug 29, 2014·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Fu-Sheng WangHong-Yang Wang
Sep 2, 2015·Antimicrobial Agents and Chemotherapy·Kyle D SmithUNKNOWN ASTRO-CM/COAT Team
Sep 24, 2015·Seminars in Respiratory and Critical Care Medicine·C C ChangS C-A Chen
Oct 6, 2016·Open Forum Infectious Diseases·John F FisherWilliam B Davis
Nov 22, 2016·Journal of Thoracic Disease·Kaixiong LiuJieming Qu
Nov 1, 2017·Medical Mycology·Y SenghorC Hennequin
Jul 14, 2015·Journal of Fungi·Ghady Haidar, Nina Singh
Oct 18, 2018·Medical Mycology·Findra SetianingrumDavid W Denning
Dec 6, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J Peter DonnellyPeter G Pappas

❮ Previous
Next ❯

Citations

May 18, 2021·Therapeutic Advances in Infectious Disease·Lauryn NsengaFelix Bongomin
Jul 10, 2021·Curēus·Kalasekhar VijayasekharanVishwapriya M Godkhindi

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
bronchoalveolar lavage
BAL
bronchoalveolar
surgical resection

Software Mentioned

SPSS®

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Advances in Hematology & Oncology : H&O
Klaus Warnatz
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
A Chakrabarti, V Gupta
International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Sasisopin KiertiburanakulSomnuek Sungkanuparph
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
L A ChenY N Liu
© 2022 Meta ULC. All rights reserved