Clonal change of methicillin-resistant Staphylococcus aureus isolated from patients with impetigo in Kagawa, Japan

The Journal of Dermatology
Nao SasaiNorihisa Noguchi

Abstract

Recently, the USA300 clone, which is a Panton-Valentine leukocidin (PVL)-positive clonal complex 8-staphylococcal cassette chromosome mec type IV (CC8-IV) community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) strain, emerged in community and hospital settings in Japan. Hence, clonal types of CA-MRSA strains are predicted to be changing. Nonetheless, long-term surveillance of CA-MRSA has not been conducted in Japan. Here, we investigated the transition and current status of CA-MRSA strains isolated from outpatients with impetigo; the samples were collected between 2007 and 2016 in Kagawa, Japan. The detection rate (22.8%, 488/2139 strains) of MRSA slightly decreased in these 10 years. Molecular epidemiological analyses showed that the prevalence of the CC89-II clone, which is a typical CA-MRSA genotype of causative agents of impetigo, significantly decreased from 48.0% (48/100 strains) in 2007-2009 to 21.9% (16/73 strains) in 2013-2016. By contrast, a non-USA300 CC8-IV clone, which is a highly pathogenic CA-MRSA/J clone, significantly increased in prevalence from 9.0% (9/100 strains) to 32.9% (24/73 strains). The prevalence of PVL-positive CA-MRSA strains increased annually from 2012 (0%) to 2015 (6.7%), where...Continue Reading

References

Jan 11, 2000·Clinical Microbiology Reviews·M M DingesP M Schlievert
Jun 5, 2002·Lancet·Tadashi BabaKeiichi Hiramatsu
Dec 25, 2002·Antimicrobial Agents and Chemotherapy·P D FeyP M Schlievert
Apr 28, 2005·The Lancet Infectious Diseases·Nicola ZetolaWilliam R Bishai
Jul 1, 2008·Trends in Microbiology·Binh An Diep, Michael Otto
Jul 18, 2009·The Journal of Antimicrobial Chemotherapy·Fred C Tenover, Richard V Goering
Jul 17, 2010·Nature Reviews. Microbiology·Richard P NovickJose R Penadés
Jul 29, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A-P MagiorakosD L Monnet
Sep 29, 2011·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Ayako NakamuraAkimichi Ohsaka
May 1, 2010·Toxins·Michal BukowskiGrzegorz Dubin
Feb 22, 2012·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Yasuhisa IwaoTatsuo Yamamoto
Mar 28, 2012·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·G R Nimmo
Apr 29, 2014·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Hidemasa NakaminamiSusumu Nishinarita
May 30, 2017·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Shunsuke TakadamaNorihisa Noguchi
Jun 29, 2017·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Hidemasa NakaminamiNorihisa Noguchi
Sep 7, 2017·FEMS Microbiology Letters·Hidemasa NakaminamiNorihisa Noguchi
Feb 13, 2018·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Atsuko TsutsuiKeigo Shibayama
Apr 10, 2018·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Dai HaradaNorihisa Noguchi
Apr 21, 2018·Journal of Medical Microbiology·Hidemasa NakaminamiNorihisa Noguchi
Oct 4, 2018·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Hidemasa NakaminamiNorihisa Noguchi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Related Papers

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Dai HaradaNorihisa Noguchi
Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Hidemasa NakaminamiNorihisa Noguchi
Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
Shunsuke TakadamaNorihisa Noguchi
Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Hidemasa NakaminamiNorihisa Noguchi
© 2022 Meta ULC. All rights reserved