Clonal haematopoiesis and COVID-19: A possible deadly liaison

International Journal of Immunogenetics
Velizar Shivarov, Milena Ivanova

Abstract

We provide evidence for a linear correlation between the frequency of clonal haematopoiesis and COVID-19 mortality rate. We discuss the mechanistic explanations for this association mediated by a pathological inflammatory response. Our hypothesis can be tested in COVID-19-infected patients and eventually lead to new approaches to risk stratification and therapy.

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Citations

Aug 20, 2020·American Journal of Human Genetics·Marissa LoPrestiBenjamin D Solomon
Dec 26, 2021·Scientific Reports·Mustafa YalcinkayaAlan R Tall

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