Clonal identity between skin and synovial tissue in a case of mycosis fungoides with polyarthritis

Journal of the American Academy of Dermatology
Yorick SandbergFreerk Heule

Abstract

Polyarthritis in the presence of a cutaneous T-cell lymphoma is a rare phenomenon. We describe a case of mycosis fungoides with development of a symmetric erosive polyarthritis of the small hand joints and feet, diagnosed as rheumatoid arthritis. An identical monoclonal T-cell population in the skin and in the synovium was detected by T-cell receptor gene rearrangement analysis, illustrating articular dissemination of lymphoma cells. Differentiating mycosis fungoides-associated arthritis from rheumatoid arthritis may have important implications for treatment. Based on this case, the relevant literature, and the newest disease concepts, pathogenic mechanisms and therapeutic options of mycosis fungoides-associated arthritis are discussed.

References

Apr 1, 1979·Arthritis and Rheumatism·M GottliebS Strober
Sep 1, 1977·Archives of Dermatology·K E GreerC E Hess
Apr 1, 1991·Annals of Internal Medicine·R G BergerT Reichert
Jun 1, 1990·Human Immunology·M K ChatilaJ T Kurnick
Oct 1, 1988·Arthritis and Rheumatism·R G Berger
Jan 1, 1972·Naika. Internal medicine·H IkemotoK Sagawa
Dec 1, 1995·Clinical Immunology and Immunopathology·P P TakF C Breedveld
Aug 1, 1994·Seminars in Arthritis and Rheumatism·T I EvansK M Sanders
Nov 1, 1993·Leukemia & Lymphoma·J TachibanaS Konda
Jan 1, 1997·Dermatology : International Journal for Clinical and Investigative Dermatology·V SigurdssonW A van Vloten
Jun 3, 1999·The British Journal of Dermatology·S Imai, H Umezu
Jun 12, 1999·Journal of the American Academy of Dermatology·E DiamandidouR Kurzrock
Apr 18, 2000·Archives of Dermatology·R van DoornR Willemze
Jan 9, 2001·Dermatology : International Journal for Clinical and Investigative Dermatology·E HodakM David
Jan 10, 2001·Current Opinion in Rheumatology·J E Naschitz
Mar 22, 2001·The New England Journal of Medicine·E H Choy, G S Panayi
Feb 13, 2003·Journal of the American Academy of Dermatology·Walter MacheinerRobert M Knobler
Jul 10, 2004·Journal of the American Academy of Dermatology·Yorick SandbergFreerk Heule

❮ Previous
Next ❯

Citations

Jul 10, 2004·Journal of the American Academy of Dermatology·Yorick SandbergFreerk Heule
May 5, 2018·International Journal of Dermatology·Ai KuzumiShinichi Sato
Jul 6, 2021·Indian Journal of Dermatology, Venereology and Leprology·Hatice Erdi SanliBanu Farabi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Related Papers

Journal of the European Academy of Dermatology and Venereology : JEADV
J-S LeeS-C Lee
Clinical and Experimental Dermatology
K J MischR A Marsden
Clinical and Experimental Dermatology
S H WakelinM Turner
© 2022 Meta ULC. All rights reserved