PMID: 6972357Nov 15, 1980Paper
Clonal origin and trisomy of chromosome 15 in murine B-cell malignancies
International Journal of Cancer. Journal International Du Cancer
P J FialkowJ I Bryant
Abstract
During the course of a multifaceted study of clonality in murine neoplasms we observed two B-lymphoid malignancies. Results of studies with the X-chromosome-linked enzyme phosphoglycerate kinase strongly suggest that these tumors had a clonal origin. Each of them had trisomy 15. This chromosomal abnormality has been found consistently in many murine thymic neoplasms, and has been thought to be specific to tumors of thymic origin. However, the occurrence of trisomy 15 in each of the only two B-cell malignancies thus far detected in our studies indicates that it may occur in B-lymphoid progenitors as well.
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Citations
Jan 1, 1982·Journal of Cancer Research and Clinical Oncology·E W Herbst, A Gropp
Jul 15, 1985·Virology·M I MallyM Haas
Feb 1, 1982·Cancer Genetics and Cytogenetics·M Sasaki
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Jan 18, 2006·The Journal of Investigative Dermatology·Ori ShulmanEitan Friedman
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