PMID: 6972357Nov 15, 1980Paper

Clonal origin and trisomy of chromosome 15 in murine B-cell malignancies

International Journal of Cancer. Journal International Du Cancer
P J FialkowJ I Bryant

Abstract

During the course of a multifaceted study of clonality in murine neoplasms we observed two B-lymphoid malignancies. Results of studies with the X-chromosome-linked enzyme phosphoglycerate kinase strongly suggest that these tumors had a clonal origin. Each of them had trisomy 15. This chromosomal abnormality has been found consistently in many murine thymic neoplasms, and has been thought to be specific to tumors of thymic origin. However, the occurrence of trisomy 15 in each of the only two B-cell malignancies thus far detected in our studies indicates that it may occur in B-lymphoid progenitors as well.

References

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Citations

Jun 1, 1983·Cancer Genetics and Cytogenetics·S S BoggsD F Saxe
Mar 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·M HaasO W Jones
Jan 18, 2006·The Journal of Investigative Dermatology·Ori ShulmanEitan Friedman
Jun 15, 1989·International Journal of Cancer. Journal International Du Cancer·W L VasmelR M Slater
Oct 15, 1982·International Journal of Cancer. Journal International Du Cancer·F CarbonellL Kreja
Dec 1, 1981·International Journal of Cancer. Journal International Du Cancer·E W HerbstC Tietgen
Nov 15, 1982·International Journal of Cancer. Journal International Du Cancer·R DzarlievaN F Fusenig
Sep 1, 1984·Journal of Clinical Pathology·A C BestedJ S Senn
Mar 15, 1987·International Journal of Cancer. Journal International Du Cancer·L TrakhtenbrotN Haran-Ghera

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