Clonal Relationships Between Malignant Lymphomas and Histiocytic/Dendritic Cell Tumors

Surgical Pathology Clinics
Andrew L Feldman

Abstract

Tumors of histiocytic or dendritic cell origin appear to occur with increased frequency in patients with lymphoma. Recent molecular data have demonstrated clonal relationships between the lymphoma and the histiocytic/dendritic cell tumor in some of these cases. Clinical, pathologic, and experimental data suggest that this phenomenon probably represents transdifferentiation of the lymphoma clone to a histiocytic/dendritic cell lineage in most cases. Awareness of this entity is necessary to prompt comparative molecular studies in appropriate cases.

References

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Citations

Aug 8, 2018·The American Journal of Dermatopathology·Salma MachanSocorro María Rodríguez-Pinilla
Jul 12, 2017·Virchows Archiv : an International Journal of Pathology·Fabio FacchettiFalko Fend

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