Cloning and embryonic expression of five distinct sfrp genes in the zebrafish Danio rerio

Gene Expression Patterns : GEP
Christian Tendeng, Corinne Houart

Abstract

Recently, a new member of the secreted frizzled-related protein (sFRP) family, named tlc, has been identified as expressed by the anterior neural border (ANB) cells in the zebrafish Danio rerio. Tlc plays an important role in telencephalic induction and patterning. In absence of Tlc, formation of the telencephalon is severely delayed, but not abolished. This prompted us to clone the other zebrafish sfrp family members and analyse their expression patterns, in search of a family member that may partly functionally overlap with Tlc. Except sizzled, expression profile of sfrp genes in zebrafish has not been reported so far. Here, we describe the cloning of full-length cDNA for sfrp1a, sfrp1b, sfrp2, sfrp3 and sfrp5 gene transcripts and we examine their expression at different embryonic stages. Only sfrp1a is expressed in the anterior neural plate including the ANB cells where and when tlc is expressed. Interestingly, compared to both tlc and sfrp1a, wnt genes are complementary expressed more posteriorly in the neural plate. Later, both sfrp1a and sfrp5 expression profiles are overlapping, in particular at pharyngula stage these genes are expressed in the ventral part of the forebrain, midbrain and hindbrain. sfrp1b, sfrp2 and sfrp...Continue Reading

References

Dec 1, 1996·Computer Applications in the Biosciences : CABIOS·N GaltierC Gautier
Nov 30, 1998·Science·A AmoresJ H Postlethwait
Nov 24, 1999·Mechanisms of Development·D DuprezN Le Douarin
Oct 12, 2000·Mechanisms of Development·P EsteveP Bovolenta
Mar 10, 2001·Nature·E S LanderUNKNOWN International Human Genome Sequencing Consortium
Sep 5, 2002·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Steve E Jones, Catherine Jomary
Dec 6, 2002·Nature·UNKNOWN Mouse Genome Sequencing ConsortiumEric S Lander
Feb 20, 2003·Developmental Biology·Arne C LekvenRandall T Moon
May 31, 2003·Journal of Cell Science·Yoshiaki Kawano, Robert Kypta
Mar 3, 2004·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Susan C ChapmanAndrew Lumsden
May 19, 2004·Mechanisms of Development·Gerri R BucklesArne C Lekven
Jun 24, 2004·Mechanisms of Development·Pilar EstevePaola Bovolenta
Apr 16, 2005·Nature Reviews. Neuroscience·Lorenza Ciani, Patricia C Salinas
May 10, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Caroline KempLuc Leyns
Sep 21, 2005·Nature Neuroscience·Josana RodriguezPaola Bovolenta

❮ Previous
Next ❯

Citations

Sep 14, 2011·Proceedings of the National Academy of Sciences of the United States of America·Fu-I LuBernard Thisse
May 12, 2011·Integrative and Comparative Biology·Sylvie Rétaux, Shungo Kano
Jan 5, 2012·BMC Genomics·Luis A MillaVerónica Palma
Oct 9, 2013·EvoDevo·Linda Z HollandJr-Kai Yu
Aug 1, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Naoki NakayaStanislav I Tomarev
Apr 16, 2008·Gene Expression Patterns : GEP·Lars WittlerMichael Kessel
Dec 17, 2009·Cell·Christian P Petersen, Peter W Reddien
Jun 10, 2009·Developmental Neurobiology·Jose Maria RuizPaola Bovolenta
Jun 22, 2011·Developmental Neurobiology·Florencia Cavodeassi, Corinne Houart
Feb 20, 2014·Genesis : the Journal of Genetics and Development·Ryan Range
May 23, 2015·Seminars in Cell & Developmental Biology·Bernard Thisse, Christine Thisse
Sep 23, 2014·Developmental Biology·Lei FengFlorence L Marlow
Jan 25, 2014·Developmental Biology·Vanessa L HollyAndrew J Waskiewicz
Aug 11, 2007·Developmental Biology·Terence J Van RaayLilianna Solnica-Krezel
Jan 16, 2007·Neuroscience Letters·Hyung-Seok KimTae-Lin Huh
Nov 20, 2012·Osteoarthritis and Cartilage·R E MitchellC L Hammond
Jun 11, 2017·Cold Spring Harbor Perspectives in Biology·Joseph ZinskiMary C Mullins
Mar 9, 2018·Frontiers in Neuroscience·Florence A Giger, Corinne Houart
Jan 27, 2019·Scientific Reports·Odete GonçalvesJonathan M Wilson
Mar 7, 2008·Journal of Cell Science·Paola BovolentaJavier Lopez-Rios
Apr 28, 2021·Molecular Biology and Evolution·Christine HirschbergerJ Andrew Gillis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.