PMID: 11311941Apr 20, 2001Paper

Cloning and expression analysis of a cDNA that encodes a leech hemerythrin

Biochimica Et Biophysica Acta
L CoutteJ L Baert

Abstract

We report the cDNA sequence of a leech hemerythrin. A cDNA was isolated from a Theromyzon tessulatum cDNA library and encodes a 120 amino acid protein of about 14 kDa. The predicted protein contains the hemerythrin signature sequence and the iron ligand residues previously identified in crystal structures of hemerythrin and myohemerythrin. The protein displayed the highest identity to myohemerythrin, a non-heme iron-binding protein described in sipunculids. Expression analysis indicated that the mRNA is widely expressed in leech and is stage specific in appearance, being absent after the two first blood meals, appearing after the last blood meal during the period preceding oogenesis and disappearing after egg laying.

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Citations

Dec 20, 2005·Journal of Molecular Evolution·Stefano VaninBenedetto Salvato
Sep 4, 2008·BMC Evolutionary Biology·Xavier BaillySerge N Vinogradov
Dec 18, 2007·FEMS Microbiology Letters·Christopher E FrenchF Bruce Ward
Aug 16, 2016·Cellular and Molecular Life Sciences : CMLS·Christopher J Coates, Heinz Decker
Oct 11, 2017·Genome Biology and Evolution·Elisa M Costa-PaivaKenneth M Halanych
Jun 23, 2005·Omics : a Journal of Integrative Biology·Maria Esther Ricci-SilvaAna Marisa Chudzinski-Tavassi
Jan 26, 2020·Proceedings of the National Academy of Sciences of the United States of America·Michelle E ClayDeborah A Hogan
Mar 24, 2017·BMC Evolutionary Biology·Elisa M Costa-PaivaKenneth M Halanych
Feb 24, 2004·The Journal of Experimental Biology·Sylvain DemuynckAlain Leprêtre

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