Cloning and expression kinetics of porcine vascular cell adhesion molecule

Biochemical and Biophysical Research Communications
Y T TsangM K Robinson

Abstract

Human vascular cell adhesion molecule is believed to play a key role in recruiting leukocytes to sites of injury. Here we report the identification of a homologous molecule in the pig which has five Ig domains and an overall 77% homology with the human protein. The expression of this protein was also characterised on porcine endothelial cells. Like the human adhesion molecule, the porcine protein could be induced by LPS, TNF and IL-1 alpha, although differences were noted in the kinetics of expression.

Citations

Jun 24, 1999·Hybridoma·C RichardJ F Bouhours
Oct 3, 1999·Xenotransplantation·A S CarterS V Fuggle
Jan 23, 2009·Veterinary Immunology and Immunopathology·Wasin Charerntantanakul
Jul 22, 2008·Veterinary Research·Laurence Piriou-Guzylack, Henri Salmon
Apr 17, 2004·Transplantation·Deirdre A CunninghamGillian A Langford
Jun 8, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·N C Kirkiles-SmithG Tellides
Mar 8, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·C J StockerD O Haskard

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